Floating Hospital for Children at Tufts Medical Center, 800 Washington Street # 344 Boston, MA 02111, Boston, Massachusetts.
Floating Hospital for Children at Tufts Medical Center, 800 Washington Street # 344 Boston, MA 02111, Boston, Massachusetts.
Clin Ther. 2018 Oct;40(10):1648-1654. doi: 10.1016/j.clinthera.2018.08.013. Epub 2018 Sep 18.
The long-term morbidity of obesity in adolescents is well recognized nationally and represents a major health concern for the population of the near future. Traditional medical management of obesity focuses on addressing behavioral modification, dietary and exercise programs, and, to a lesser degree, pharmaceuticals. Although these strategies are relatively effective, they suffer from the lack of sustained benefit, a high relapse rate, and, in case of pharmacotherapy, potentially dangerous adverse effects. Bariatric surgery in adolescents has often been characterized as a risky intervention with unknown long-term benefits. However, recent data establish that a sustained, clinically meaningful effect on weight loss, as well as a reduction in chronic morbidities related to obesity, can be achieved. The role of bariatric surgery as an accepted adjunctive strategy in the treatment of obesity in adolescents is becoming more recognized; however, a number of barriers exist that prevent the timely evaluation of adolescents with obesity for potential surgical intervention. We examine these barriers in light of recent advancements to help better define the role of bariatric surgery in the treatment of obesity in adolescent population.
青少年肥胖的长期发病率在全国范围内已得到广泛认识，这是未来人口健康的主要关注点。传统的肥胖医学管理方法侧重于解决行为改变、饮食和运动计划，以及在较小程度上的药物治疗。尽管这些策略相对有效，但它们存在缺乏持续受益、高复发率的问题，而且在药物治疗的情况下，还可能产生潜在的危险副作用。青少年的减肥手术通常被认为是一种风险干预措施，其长期益处未知。然而，最近的数据表明，减肥手术可以实现持续的、具有临床意义的体重减轻效果，同时减少与肥胖相关的慢性并发症。减肥手术作为青少年肥胖治疗的一种公认的辅助策略的作用正越来越被认可；然而，仍然存在一些障碍，阻碍了对肥胖青少年进行潜在手术干预的及时评估。我们根据最近的进展情况来研究这些障碍，以更好地确定减肥手术在青少年肥胖治疗中的作用。
