马来西亚半岛巨细胞病毒和单纯疱疹病毒感染的血清学研究。
A serological study of cytomegalovirus and herpes simplex virus infections in Peninsular Malaysia.
作者信息
Tan D S, Stern H
出版信息
Bull World Health Organ. 1981;59(6):909-12.
Healthy Malaysians from various parts of Peninsular Malaysia were examined for CF antibodies against cytomegalovirus (CMV) and herpes simplex virus (HSV) type 2. CMV antibodies were detected in 1114 out of 1556 persons (71.6%) and HSV antibodies were detected in 954 persons out of 1554 (61.4%). The age distribution patterns were similar for the two infections, with maximum prevalence at 5 - 14 years of age. Prevalence was higher in women than in men. There were no significant differences among the Malay, Chinese, and Indian groups of the population with respect to CMV, 72 - 78% possessing antibodies, but in the case of HSV, 76% of the Chinese had antibodies, compared with 57 - 60% of the Malays and Indians. More than 90% of newborn infants had CMV and HSV CF antibodies, confirming the highly immune status of childbearing women in Malaysia. No CMV-specific IgM was detected in the Malaysian neonates examined but this does not exclude the possibility of congenital infection.
对来自马来西亚半岛各地的健康马来西亚人进行了针对巨细胞病毒（CMV）和2型单纯疱疹病毒（HSV）的补体结合（CF）抗体检测。在1556人中，有1114人（71.6%）检测到CMV抗体；在1554人中，有954人（61.4%）检测到HSV抗体。两种感染的年龄分布模式相似，在5至14岁时患病率最高。女性的患病率高于男性。在CMV方面，马来族、华族和印族人群之间没有显著差异，72%至78%的人拥有抗体，但在HSV方面，76%的华人有抗体，而马来人和印度人分别为57%至60%。超过90%的新生儿有CMV和HSV的CF抗体，证实了马来西亚育龄妇女的高免疫状态。在所检测的马来西亚新生儿中未检测到CMV特异性IgM，但这并不排除先天性感染的可能性。
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