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男性饮食中脂肪、蛋白质、胆固醇和纤维摄入量与致动脉粥样硬化脂蛋白的关系。

Relationship of dietary fat, protein, cholesterol, and fiber intake to atherogenic lipoproteins in men.

作者信息

Williams P T, Krauss R M, Kindel-Joyce S, Dreon D M, Vranizan K M, Wood P D

出版信息

Am J Clin Nutr. 1986 Dec;44(6):788-97. doi: 10.1093/ajcn/44.6.788.

DOI:10.1093/ajcn/44.6.788
PMID:3024477
Abstract

Nutritional components (g/1000 kcal) obtained from 3-day diet records are compared to triglyceride, total cholesterol, low-density (LDL), intermediate-density (IDL), and very low-density (VLDL) lipoprotein concentrations of 77 free-living men. Polyunsaturated-fatty acid consumption correlated negatively with concentrations of triglycerides, total cholesterol, LDL- and VLDL-cholesterol, and total-lipoprotein mass of smaller-LDL particles (Sf0 0-7), IDL (Sf0 12-20), and VLDL (Sf0 20-400) in serum and plasma. Animal-protein consumption correlated positively and plant-protein consumption correlated negatively with triglycerides, smaller-LDL mass, VLDL-cholesterol, and VLDL-mass levels. Serum concentrations of smaller-LDL particles were also positively correlated with dietary-cholesterol intake and negatively correlated with crude-fiber consumption. Thus, diet-lipoprotein relationships observed cross-culturally and experimentally are further supported when detailed dietary measurements from 3-day diet records and lipoprotein measurements from repeated blood samplings are correlated in free-living men.

摘要

将从3天饮食记录中获取的营养成分(克/1000千卡)与77名自由生活男性的甘油三酯、总胆固醇、低密度(LDL)、中密度(IDL)和极低密度(VLDL)脂蛋白浓度进行比较。多不饱和脂肪酸的摄入量与血清和血浆中甘油三酯、总胆固醇、LDL和VLDL胆固醇的浓度以及较小LDL颗粒(Sf0 0 - 7)、IDL(Sf0 12 - 20)和VLDL(Sf0 20 - 400)的总脂蛋白质量呈负相关。动物蛋白的摄入量与甘油三酯、较小LDL质量、VLDL胆固醇和VLDL质量水平呈正相关,而植物蛋白的摄入量与这些指标呈负相关。较小LDL颗粒的血清浓度也与膳食胆固醇摄入量呈正相关,与粗纤维摄入量呈负相关。因此,当将自由生活男性3天饮食记录中的详细膳食测量数据与重复采血的脂蛋白测量数据进行关联时,跨文化和实验观察到的饮食与脂蛋白之间的关系得到了进一步支持。

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Dietary interventions (plant sterols, stanols, omega-3 fatty acids, soy protein and dietary fibers) for familial hypercholesterolaemia.针对家族性高胆固醇血症的饮食干预措施(植物甾醇、甾烷醇、ω-3脂肪酸、大豆蛋白和膳食纤维)。
Cochrane Database Syst Rev. 2014 Jun 10;2014(6):CD001918. doi: 10.1002/14651858.CD001918.pub3.
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A butter diet induces higher levels of n-3 PUFA and of n-3/n-6 PUFA ratio in rat serum and hearts than a safflower oil diet.
与红花油饮食相比,黄油饮食会使大鼠血清和心脏中的 n-3 PUFA 和 n-3/n-6 PUFA 比值升高。
Environ Health Prev Med. 2001 Jan;5(4):138-43. doi: 10.1007/BF02918289.
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Health effects and prevalence of vegetarianism.素食主义对健康的影响及流行程度。
West J Med. 1994 May;160(5):465-70.
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