PAHSA 研究的复杂性。
On the Complexity of PAHSA Research.
机构信息
Department of Adipose Tissue Biology, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
出版信息
Cell Metab. 2018 Oct 2;28(4):541-542. doi: 10.1016/j.cmet.2018.09.006. Epub 2018 Sep 20.
PMID:30244970
Abstract
Reporting in Cell Metabolism, Pflimlin et al. recently found no beneficial effect of PAHSAs on glucose control in mice on several high-fat diets. Kuda cautions that due to methodological differences, the data must be carefully reinterpreted, emphasizing that olive oil contains high amounts of FAHFAs, potentially masking the effects of PAHSAs in studies utilizing this vehicle.
摘要
在《细胞代谢》杂志上，Pflimlin 等人最近发现，在几种高脂肪饮食中，PAHSA 对小鼠的葡萄糖控制没有有益作用。Kuda 警告说，由于方法学上的差异，必须仔细重新解释这些数据，并强调橄榄油含有大量的 FAHFA，这可能掩盖了在使用这种载体的研究中 PAHSA 的作用。
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