Yoshida Takashi, Hayami Yutaro, Yoshida Kenji, Kinoshita Hidefumi, Matsuda Tadashi
Department of Urology and Andrology, Graduate School of Medicine, Kansai Medical University, Osaka, Japan.
J Cancer Res Ther. 2018 Sep;14(Supplement):S803-S805. doi: 10.4103/0973-1482.175433.
Choriocarcinoma syndrome is a life-threatening lysis syndrome caused by blood vessel rupture and subsequent tumor bleeding. We describe a case of pretreatment choriocarcinoma syndrome that developed in a 27-year-old man. He underwent a high orchiectomy at a local hospital and was diagnosed with metastatic testicular tumor given the high serum human chorionic gonadotropin levels (943,601 mIU/mL). Thus, he was referred to our institution. Although he had bulky lung metastases and alveolar bleeding, we were able to administer full-dose chemotherapy with etoposide and cisplatin. On day 3 of chemotherapy, he presented with severe hypoxia and worsening of alveolar bleeding. Thus, he underwent tracheal intubation at the Intensive Care Unit. Full-dose chemotherapy was continued, and the patient was extubated upon improvement. He is currently alive and continuing treatment at another hospital.
绒毛膜癌综合征是一种由血管破裂及随后的肿瘤出血引起的危及生命的溶解综合征。我们描述了一例发生在一名27岁男性身上的治疗前绒毛膜癌综合征病例。他在当地一家医院接受了高位睾丸切除术，鉴于血清人绒毛膜促性腺激素水平较高（943,601 mIU/mL），被诊断为转移性睾丸肿瘤。因此，他被转诊至我们机构。尽管他有大量肺转移灶和肺泡出血，但我们仍能够用依托泊苷和顺铂进行全剂量化疗。化疗第3天，他出现严重缺氧，肺泡出血加重。因此，他在重症监护病房接受了气管插管。全剂量化疗继续进行，患者病情好转后拔管。他目前还活着，正在另一家医院继续接受治疗。
