Luo Fan, Feng Fei, Zhao Bin, Tian Bowen, Yang Xuelei, Zhou Haimei, Li Xinxin
Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Se Pu. 2018 Sep 8;36(9):911-916. doi: 10.3724/SP.J.1123.2018.03037.
Miniaturization of gas chromatography (GC) columns is one of the key problems associated with microminiaturization of a chromatograph. In this study, a GC column with high-aspect-ratio microchannel based on micro-electro-mechanical system (MEMS) technology has been designed and manufactured. Simulation and analysis by the COMSOL software revealed that the GC column has even velocity field distribution, which is crucial for improving the separation efficiency of the column. The results show that heavy hydrocarbons (C6-C10) and compounds of benzene series can be successfully separated. The number of theoretical plate is 14028 plates/m, and the resolution of C7-C8 is 10.82. Due to its advantages of smaller volume, lower energy consumption, and better separation performance, the GC column can be applied in micro gas chromatography.
气相色谱(GC)柱的微型化是与色谱仪微缩化相关的关键问题之一。在本研究中,基于微机电系统(MEMS)技术设计并制造了一种具有高纵横比微通道的GC柱。通过COMSOL软件进行的模拟和分析表明,该GC柱具有均匀的速度场分布,这对于提高柱的分离效率至关重要。结果表明,重烃(C6 - C10)和苯系化合物能够成功分离。理论塔板数为14028块/米,C7 - C8的分离度为10.82。由于其体积更小、能耗更低以及分离性能更好的优点,该GC柱可应用于微型气相色谱。