Research Group Neuroinflammation and Mucosal Immunology, Max Planck Institute of Biochemistry, Martinsried, Germany.
Front Immunol. 2018 Sep 11;9:2067. doi: 10.3389/fimmu.2018.02067. eCollection 2018.
Commensal gut microbiota exerts multifarious effects on intestinal and extra-intestinal immune homeostasis. A disruption in the microbial composition of the gut has been associated with many neurological disorders with inflammatory components. Here we review known associations between gut microbiota and neurological disorders. Further we highlight the emerging role of diet and microbiota interrelationship in regulating neuroinflammation.
共生肠道微生物群对肠道和肠道外免疫稳态发挥着多样的作用。肠道微生物组成的破坏与许多具有炎症成分的神经紊乱有关。在这里,我们回顾了肠道微生物群与神经紊乱之间的已知关联。此外,我们还强调了饮食和微生物相互关系在调节神经炎症中的新作用。