Otsyina H R, Mbuthia P G, Nguhiu-Mwangi J, Mogoa E G M, Ogara W O
School of Veterinary Medicine, College of Basic and Applied Sciences, University of Ghana, Legon, Ghana.
Department of Clinical Studies, Faculty of Veterinary Medicine, University of Nairobi, Kenya.
Int J Vet Sci Med. 2017 Nov 9;5(2):152-158. doi: 10.1016/j.ijvsm.2017.08.005. eCollection 2017 Dec.
The objective of this study was to evaluate the gross and histo-pathological lesions caused by plastic bags in the rumen of sheep. Sixteen (16) castrated, one-year old Dorper sheep were used for the study. The animals were divided into 4 groups each consisting of 4 sheep. Three of the groups had 129 g, 258 g and 387 g of plastic bags, respectively, introduced into the rumen through rumenotomy, while the fourth group, without implants served as control. All the animals were observed daily for 6 weeks following implantation. All animals were euthanized on day 42 and subjected to gross and histopathological examination. Gross changes observed at post mortem included; atrophy of the muscle and body fat, atrophy and fibrosis of the spleen, liver, kidneys and hydropericardium. Gross lesions in the rumen included stunting, atrophy, thinning and loss of ruminal papillae, erosion, ulcerations and nodular formation on the ruminal mucosa. Histopathological examination revealed atrophy, ulceration, erosion and disruptions of the stratified epithelial layer of the papillae. Other changes included parakeratosis, hyperkeratosis, prominent rete pegs, oedema and severe hydropic degeneration of different parts of the mucosal layer. There was increased mononuclear cell infiltration, increase in the number of lymphatic vessels and lymphangiectasis in the submucosa and oedema in the muscularis and serosal layers. The pathological changes observed contributed to clinical signs and may interfere with the absorption of nutrients resulting in poor condition of the animal, and loss of production and productivity.
本研究的目的是评估塑料袋对绵羊瘤胃造成的大体和组织病理学损伤。选用16只一岁的去势多珀绵羊进行本研究。将这些动物分为4组，每组4只羊。其中3组分别通过瘤胃切开术向瘤胃内植入129克、258克和387克塑料袋，而第4组不植入作为对照。植入后每天观察所有动物6周。在第42天对所有动物实施安乐死，并进行大体和组织病理学检查。尸检时观察到的大体变化包括：肌肉和体脂萎缩、脾脏、肝脏、肾脏萎缩和纤维化以及心包积水。瘤胃的大体损伤包括发育迟缓、萎缩、变薄和瘤胃乳头缺失、瘤胃黏膜糜烂、溃疡和结节形成。组织病理学检查显示乳头分层上皮层萎缩、溃疡、糜烂和破坏。其他变化包括角化不全、角化过度、 rete钉突突出、水肿以及黏膜层不同部位的严重水样变性。黏膜下层单核细胞浸润增加、淋巴管数量增多和淋巴管扩张，肌层和浆膜层水肿。观察到的病理变化导致了临床症状，并可能干扰营养物质的吸收，从而使动物状况不佳，生产性能下降。
