Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands.
Department of Radiology and Nuclear Medicine, Meander Medical Centre, Maatweg 3, 3813 TZ, Amersfoort, The Netherlands.
Eur Radiol. 2019 Mar;29(3):1408-1414. doi: 10.1007/s00330-018-5740-4. Epub 2018 Sep 25.
Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lung perfusion in CT pulmonary angiography (CTPA) in patients with suspicion of acute and chronic pulmonary embolism, with acceptable radiation dose. This paper discusses the technical principles, clinical interpretation, benefits and limitations of arterial subtraction CTPA. KEY POINTS: • SCT uses motion correction and image subtraction between an unenhanced and an enhanced CT scan to obtain iodine distribution in the pulmonary parenchyma. • SCT could have an added value in detection of pulmonary embolism. • SCT requires only software implementation, making it potentially more widely available for patient care than dual-energy CT.
减影 CT(SCT)是一种利用未增强和增强 CT 扫描之间基于软件的运动校正技术,以获取肺实质中的碘分布。该技术已在临床实践中用于评估怀疑患有急性和慢性肺栓塞的 CT 肺动脉造影(CTPA)中的肺灌注,辐射剂量可接受。本文讨论了动脉减影 CTPA 的技术原理、临床解读、益处和局限性。
SCT 使用运动校正和未增强与增强 CT 扫描之间的图像减影来获取肺实质中的碘分布。
SCT 在检测肺栓塞方面可能具有附加价值。
SCT 仅需要软件实现,使其比双能 CT 更有可能广泛应用于患者护理。