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黑腹果蝇中P因子转导的hsp - 28基因的染色质结构。

Chromatin structure of a P-element-transduced hsp-28 gene in Drosophila melanogaster.

作者信息

Eissenberg J C, Elgin S C

出版信息

Mol Cell Biol. 1986 Nov;6(11):4126-9. doi: 10.1128/mcb.6.11.4126-4129.1986.

DOI:10.1128/mcb.6.11.4126-4129.1986
PMID:3025635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC367183/
Abstract

The Drosophila hsp-28 gene was heat inducible when transduced to novel chromosomal sites even when no direct selection for transduced gene expression was imposed. The pattern of DNase I-hypersensitive sites 5' to the wild type and transduced copy of hsp-28 was similar. In addition, DNase I-hypersensitive sites occurred within the P-element sequences flanking transduced loci.

摘要

果蝇的hsp - 28基因在转导至新的染色体位点时可被热诱导,即使没有对转导基因的表达进行直接选择。hsp - 28野生型和转导拷贝5'端的DNA酶I超敏位点模式相似。此外,DNA酶I超敏位点出现在转导位点侧翼的P - 元件序列内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/67c57bb8f5c9/molcellb00095-0572-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/3dbe8cdc159b/molcellb00095-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/a6af9c4d27e3/molcellb00095-0571-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/67c57bb8f5c9/molcellb00095-0572-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/3dbe8cdc159b/molcellb00095-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/a6af9c4d27e3/molcellb00095-0571-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/116f/367183/67c57bb8f5c9/molcellb00095-0572-a.jpg

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本文引用的文献

1
The regulatory domain of a larval serum protein gene in Drosophila melanogaster.黑腹果蝇幼虫血清蛋白基因的调控区。
EMBO J. 1985 Dec 30;4(13B):3789-95. doi: 10.1002/j.1460-2075.1985.tb04149.x.
2
The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I.染色质中果蝇热休克基因的5'端对脱氧核糖核酸酶I高度敏感。
Nature. 1980 Aug 28;286(5776):854-60. doi: 10.1038/286854a0.
3
Correct temperature induction and developmental regulation of a cloned heat shock gene transformed into the Drosophila germ line.
导入果蝇生殖系的克隆热休克基因的正确温度诱导和发育调控。
Mol Cell Biol. 1984 Dec;4(12):2883-9. doi: 10.1128/mcb.4.12.2883-2889.1984.
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New heat shock puffs and beta-galactosidase activity resulting from transformation of Drosophila with an hsp70-lacZ hybrid gene.用hsp70-lacZ杂交基因转化果蝇后产生的新热休克胀泡和β-半乳糖苷酶活性。
Cell. 1983 Dec;35(2 Pt 1):403-10. doi: 10.1016/0092-8674(83)90173-3.
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Chromatin structure in pre- and postblastula embryos of Drosophila.果蝇囊胚形成前和形成后胚胎中的染色质结构。
Dev Biol. 1983 Sep;99(1):194-201. doi: 10.1016/0012-1606(83)90267-1.
6
The normal developmental regulation of a cloned sgs3 'glue' gene chromosomally integrated in Drosophila melanogaster by P element transformation.通过P因子转化染色体整合到黑腹果蝇中的克隆sgs3“胶水”基因的正常发育调控。
EMBO J. 1983;2(12):2137-42. doi: 10.1002/j.1460-2075.1983.tb01714.x.
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Transformation of white locus DNA in drosophila: dosage compensation, zeste interaction, and position effects.果蝇中白色基因座DNA的转化:剂量补偿、朱红色基因相互作用及位置效应
Cell. 1984 Feb;36(2):469-81. doi: 10.1016/0092-8674(84)90240-x.
8
Chromatin structure and transcriptional activity of an X-linked heat shock gene in drosophila pseudoobscura.
J Biol Chem. 1983 Nov 25;258(22):13986-91.
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Vectors for P element-mediated gene transfer in Drosophila.用于果蝇中P因子介导的基因转移的载体。
Nucleic Acids Res. 1983 Sep 24;11(18):6341-51. doi: 10.1093/nar/11.18.6341.
10
Correct developmental expression of a cloned alcohol dehydrogenase gene transduced into the Drosophila germ line.转入果蝇种系的克隆乙醇脱氢酶基因的正确发育表达。
Cell. 1983 Aug;34(1):59-73. doi: 10.1016/0092-8674(83)90136-8.