人类基因：是时候走少有人走的路了？
Human genes: Time to follow the roads less traveled?
机构信息
Open Targets and European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
出版信息
PLoS Biol. 2018 Sep 26;16(9):e3000034. doi: 10.1371/journal.pbio.3000034. eCollection 2018 Sep.
Abstract
Determining the functions of human genes is a key objective for understanding disease and enabling development of new therapeutic approaches. A number of recent studies have shown that the amount of attention the research community gives to each of the more than 20,000 human genes is dramatically skewed toward specific, well-known genes. In this issue, Stoeger and colleagues uncover the factors that explain this bias and offer a way ahead to move more genes into the research limelight.
摘要
确定人类基因的功能是理解疾病和开发新治疗方法的主要目标。最近的一些研究表明，研究界对超过 20000 个人类基因的关注程度严重偏向于特定的、众所周知的基因。在本期杂志中，Stoeger 及其同事揭示了导致这种偏见的因素，并提出了一种方法，使更多的基因进入研究的焦点。
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