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住院时间与痴呆:观察性研究的系统评价。

Length of hospital stay and dementia: A systematic review of observational studies.

机构信息

Network Aging Research, University of Heidelberg, Heidelberg, Germany.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.

出版信息

Int J Geriatr Psychiatry. 2019 Jan;34(1):8-21. doi: 10.1002/gps.4993. Epub 2018 Sep 27.

Abstract

OBJECTIVE

Hospitalizations of people with dementia (PWD) are often accompanied by complications or functional loss and can lead to adverse outcomes. Unsystematic findings suggest an influence of comorbidities on the extent of differences in the length of hospital stay (LOS). This systematic review aimed to identify and evaluate all studies reporting LOS in PWD as compared to PwoD in general hospitals.

METHODS

A systematic review of observational studies using PubMed and ISI Web of Knowledge. Inclusion criteria comprised original studies written in English or German, assessment of diagnosis of dementia, measurement of LOS, and comparison of people with and without dementia.

RESULTS

Fifty-two of 60 studies reported a longer hospitalization time for PWD compared to PwoD. The extent of the difference in LOS varied between and within countries as well as by type of primary morbidity (eg, injuries, cardiovascular diseases). The range of the LOS difference for studies without restriction to a primary morbidity was -2 to +22 days after matching or adjustment for a variable number and selection of potentially relevant covariates. For studies with injuries/fractures/medical procedures and infectious/vascular disease as the primary morbidity, the range was -2.9 to +12.4 and -11.2 to +21.8 days, respectively.

CONCLUSIONS

The majority of studies reported a longer hospitalization of PWD compared to PwoD. Length of hospital stay seems to be influenced by a variety of medical, social, organizational factors, including reasons for hospital admission, whose role should be explored in detail in further research.

摘要

目的

痴呆症患者(PWD)的住院往往伴随着并发症或功能丧失,并可能导致不良后果。非系统性研究结果表明,合并症对住院时间(LOS)差异程度有影响。本系统评价旨在确定和评估所有报告一般医院 PWD 与 PwoD 之间 LOS 的研究,并对其进行评估。

方法

使用 PubMed 和 ISI Web of Knowledge 对观察性研究进行系统评价。纳入标准包括:原始研究为英文或德文,评估痴呆症诊断,测量 LOS,并比较痴呆症患者和非痴呆症患者。

结果

在 60 项研究中,有 52 项研究报告痴呆症患者的住院时间长于非痴呆症患者。 LOS 差异程度在国家之间以及国家内部、以及原发性疾病类型之间存在差异(例如,损伤、心血管疾病)。在不限制原发性疾病的情况下进行研究时,LOS 差异范围为 -2 至 +22 天,经匹配或调整潜在相关协变量的数量和选择后。对于以损伤/骨折/医疗程序和感染/血管疾病为原发性疾病的研究,范围分别为-2.9 至 +12.4 天和-11.2 至 +21.8 天。

结论

大多数研究报告痴呆症患者的住院时间长于非痴呆症患者。住院时间似乎受到多种医疗、社会、组织因素的影响,包括住院原因,这些因素在进一步研究中应详细探讨。

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