Network Aging Research, University of Heidelberg, Heidelberg, Baden-Wuerttemberg, Germany.
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany.
J Alzheimers Dis. 2019;67(3):1055-1065. doi: 10.3233/JAD-180593.
Hospital care of older adults, especially of those with dementia, is associated with a high risk of complications and increased mortality. Adverse events are often triggered by hospital-related factors, hence the time spent in hospitals should be limited. There is little knowledge of the specific factors influencing hospitalizations of older persons.
To assess the duration of length of stay (LOS) and risk factors of increased LOS, and, specifically, the role of delirium and neuropsychiatric symptoms (NPS) among a large sample of older adults with and without dementia in Germany.
A claims data based dynamic retrospective cohort study from 2004 to 2015 was conducted. People with dementia (PWD) were identified using ICD-10 codes and the application of diagnostic measures. A control group without diagnosis of dementia (CG) were matched in a 3: 1 ratio. Multivariate methods were used to investigate the factors associated with LOS.
7,139 PWD and 21,417 controls were included. PWD had longer hospitalizations (first LOS: +4.3 days; second LOS: +0.2 days) than the CG. Diagnosis of delirium was associated with LOS, both for PWD (first LOS: +9.6 days; second LOS: +5.3 days) and CG (first LOS: +13.7 days; second LOS: +7.2 days).
Major determinants of LOS were similar in PWD and the CG. The strongest association was found for the presence of delirium and NPS. Future research should focus on prevention and intervention strategies that may reduce the impact of delirium as well as NPS on the length of stay especially for PWD.
老年人,尤其是痴呆症患者的医院护理存在较高的并发症和死亡率风险。不良事件通常由与医院相关的因素引发,因此住院时间应尽量缩短。目前对于影响老年人住院的具体因素知之甚少。
评估德国大量痴呆症和非痴呆症老年患者的住院时间(LOS)和 LOS 延长的危险因素,特别是谵妄和神经精神症状(NPS)的作用。
本研究为基于索赔数据的回顾性动态队列研究,时间范围为 2004 年至 2015 年。使用 ICD-10 代码和诊断措施识别痴呆症患者(PWD)。按照 3:1 的比例与无痴呆症诊断的对照组(CG)进行匹配。使用多变量方法来研究与 LOS 相关的因素。
共纳入 7139 名 PWD 和 21417 名对照组。PWD 的住院时间较长(首次 LOS:+4.3 天;再次 LOS:+0.2 天)。痴呆症的诊断与 LOS 相关,无论是 PWD(首次 LOS:+9.6 天;再次 LOS:+5.3 天)还是 CG(首次 LOS:+13.7 天;再次 LOS:+7.2 天)。
PWD 和 CG 中 LOS 的主要决定因素相似。与 LOS 相关性最强的是谵妄和 NPS 的存在。未来的研究应重点关注预防和干预策略,这些策略可能会降低谵妄和 NPS 对住院时间的影响,特别是对 PWD。