由……产生的氨基酸衍生物的分离及抗氧化活性
Isolation and antioxidative activity of amino acid derivatives produced by .
作者信息
Lee Yu Geon, Cho Jeong-Yong, Moon Jae-Hak
机构信息
Department of Food Science and Technology and Functional Food Research Center, Chonnam National University, Gwangju, 61186 Korea.
出版信息
Food Sci Biotechnol. 2016 Feb 29;25(1):329-334. doi: 10.1007/s10068-016-0046-2. eCollection 2016.
One new phenyl lactic acid derivative, -(5-amino-2-hydroxy-1-oxopentyl)-tyrosine (), and three known metabolites [()-8-hydroxy-4-hydroxy-phenylpropanoic acid (), ()-8-hydroxy-phenylpropanoic acid (), and indole-()-3-lactic acid ()] were isolated from the culture medium of guided with DPPH radical-scavenging assay. The chemical structures of the isolated compounds were determined by NMR and electrospray ionization mass spectroscopy. The isolated four compounds were assumed to be metabolites formed by the transformation of amino acids. The DPPH radical-scavenging activities of and were significantly higher than those of and . This result may provide meaningful information of antioxidative metabolites from lactic acid bacteria.
通过DPPH自由基清除试验从 的培养基中分离出一种新的苯乳酸衍生物，-(5-氨基-2-羟基-1-氧代戊基)-酪氨酸()，以及三种已知代谢产物[()-8-羟基-4-羟基苯丙酸()、()-8-羟基苯丙酸()和吲哚-()-3-乳酸()]。通过核磁共振和电喷雾电离质谱法确定了分离出的化合物的化学结构。假定分离出的这四种化合物是由氨基酸转化形成的代谢产物。 和 的DPPH自由基清除活性显著高于 和 。该结果可能为乳酸菌抗氧化代谢产物提供有意义的信息。
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