Wienecke Antje, Kraywinkel Klaus
Abteilung für Epidemiologie und Gesundheitsmonitoring, Zentrum für Krebsregisterdaten, Robert Koch-Institut, General-Pape-Straße 62-66, 12101, Berlin, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Nov;61(11):1399-1406. doi: 10.1007/s00103-018-2821-0.
Tobacco consumption is the most important cancer risk factor. In Germany, about 15% of all new cancer cases can be attributed to smoking. The aim of this paper is to analyze the incidence and mortality trends in tobacco-associated cancer cases in Germany for the last two decades.
Age standardized incidence and mortality rates were calculated for tumors of the upper aerodigestive tract and lower urinary tract for the period from 1995 to 2014/2015. In addition, average annual percentage changes were calculated with joinpoint regression analysis. Regarding lung cancer, trends in incidence and mortality rates were also stratified by different age groups and trends in mortality rates were analyzed by birth cohorts.
The incidence and mortality rates among men are declining for all tobacco-associated cancers except esophageal cancer. Lung cancer mortality rates showed the greatest decrease with -1.9% on average per year. The incidence rates among women increased for all tobacco-associated cancers except lower urinary tract cancers. The increase in lung cancer incidence was greatest with 3.3% on average per year. Among men there was a continuous decline over all birth cohorts regarding the chance of dying of lung cancer at a certain age. Among women, the chance of dying of lung cancer increased for all birth cohorts until 1960.
The present analyses regarding tobacco-associated cancers in Germany reflect the changes in smoking prevalence with a deferment of multiple decades.
烟草消费是最重要的癌症风险因素。在德国,所有新发癌症病例中约15%可归因于吸烟。本文旨在分析德国过去二十年烟草相关癌症病例的发病率和死亡率趋势。
计算了1995年至2014/2015年期间上消化道和下泌尿道肿瘤的年龄标准化发病率和死亡率。此外,通过连接点回归分析计算了平均年度百分比变化。对于肺癌,发病率和死亡率趋势也按不同年龄组进行了分层,死亡率趋势按出生队列进行了分析。
除食管癌外,所有烟草相关癌症的男性发病率和死亡率均在下降。肺癌死亡率下降幅度最大,平均每年下降1.9%。除下泌尿道癌症外,所有烟草相关癌症的女性发病率均有所上升。肺癌发病率上升幅度最大,平均每年上升3.3%。在男性中,所有出生队列在特定年龄死于肺癌的几率持续下降。在女性中,直到1960年,所有出生队列死于肺癌的几率都在增加。
目前对德国烟草相关癌症的分析反映了吸烟流行率的变化,且有几十年的延迟。