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2010 - 2016年经济危机期间希腊医院诊断沙门氏菌病的实验室能力及监测系统的运行情况

Laboratory capacity of Greek hospitals for diagnosis of salmonellosis and surveillance systems' performance in the years of economic crisis, 2010-2016.

作者信息

Mellou K, Saranti-Papasaranti E, Mandilara G, Georgakopoulou T

机构信息

Hellenic Centre for Disease Control and Prevention, Athens, Greece.

National Reference Centre for Salmonella, National School of Public Health, Central Public Health Laboratory, Hellenic Centre for Disease Control and Prevention, Vari, Attica, Greece.

出版信息

Epidemiol Infect. 2018 Sep 28;147:e17. doi: 10.1017/S0950268818002686.

Abstract

Austerity might have affected the capacity of public hospitals in Greece to diagnose salmonellosis (laboratory capacity) over the period 2010-2016, as well as the performance of the existing surveillance systems. The scope of this paper is to present data on laboratory capacity over these years, as well as the results of a two-source capture-recapture study (data from Mandatory Notification System and National Reference Laboratory System for Salmonella). The main findings were that: (a) laboratory capacity was high and steady besides the financial crisis, (b) the estimated number of laboratory-confirmed cases (n = 6017, 95% CI 5892-6142) resulted in an incidence rate (7.9 cases/100 000 population) almost twice than that reported by the two systems Mandatory Notification System (MNS); 4.1 and National Reference Laboratory System (NRLS); 4.5 cases/100 000 population, (c) underreporting was high for both systems (MNS; 47.5% and NRLS; 42.8%) and (d) differences by geographical region, size and type of hospital were identified. We suggest that (a) specific interventions are needed to increase completeness of the systems by type of hospital and geographical region, (b) record linkage can help in estimating the disease burden in a more valid way than each system separately and (c) a common electronic database in order to feed one system to the other could significantly increase completeness of both systems.

摘要

在2010年至2016年期间,财政紧缩可能影响了希腊公立医院诊断沙门氏菌病的能力(实验室能力)以及现有监测系统的运行情况。本文的目的是呈现这些年实验室能力的数据,以及一项双源捕获 - 再捕获研究的结果(来自沙门氏菌强制报告系统和国家参考实验室系统的数据)。主要发现如下:(a)除金融危机期间外,实验室能力较高且稳定;(b)实验室确诊病例的估计数(n = 6017,95%置信区间5892 - 6142)得出的发病率(7.9例/10万人口)几乎是强制报告系统(MNS)和国家参考实验室系统(NRLS)报告发病率的两倍,MNS报告的发病率为4.1例/10万人口,NRLS报告的发病率为4.5例/10万人口;(c)两个系统的漏报率都很高(MNS为47.5%,NRLS为42.8%);(d)确定了不同地理区域、医院规模和类型之间的差异。我们建议:(a)需要采取具体干预措施,按医院类型和地理区域提高系统的完整性;(b)记录链接有助于以比单独使用每个系统更有效的方式估计疾病负担;(c)建立一个通用电子数据库,以便一个系统为另一个系统提供数据,这可以显著提高两个系统的完整性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434d/6518497/a3e185bcea4b/S0950268818002686_fig1.jpg

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