Xu Haowen, Guan Sheng, Liu Chao, Wang Li, Yan Baojun, Han Hongjie, Quan Tao
Department of Neurointerventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Neurology, Children's Hospital, Zhengzhou City, China.
World Neurosurg. 2019 Jan;121:19-23. doi: 10.1016/j.wneu.2018.09.131. Epub 2018 Sep 26.
Vessel perforation is a serious technical complication during mechanical thrombectomy (MT) for the treatment of acute ischemic stroke with large vessel occlusion. Routine rescue strategy includes balloon occlusion for tamponade, procedure suspension, and lowering or normalizing blood pressure. However, this complication is still associated with poor outcome and high mortality.
In this paper, the authors report their experience by using glue to embolize the ruptured vessel secondary to microcatheter/microwire perforation, preventing further deterioration in clinical outcome. Rescue glue embolization was attempted in 2 patients who developed intraprocedural vessel perforation while trying to gain access through the blocked artery with a microcatheter/microwire.
The ruptured vessels were effectively occluded. Stent retriever thrombectomies were then continued, and TICI 2b and 3 recanalizations were achieved. Both patients' neurologic status improved.
The key benefit of this method exists in embolizing the ruptured vessel without affecting the following MT. We propose the rescue glue embolization is simple yet effective in managing vessel perforation complication during MT.
血管穿孔是机械取栓术(MT)治疗急性大血管闭塞性缺血性卒中时一种严重的技术并发症。常规的补救策略包括球囊封堵止血、暂停手术以及降低血压或使血压正常化。然而,这种并发症仍然与不良预后和高死亡率相关。
在本文中,作者报告了他们使用胶水栓塞微导管/微导丝穿孔导致的破裂血管的经验,以防止临床结局进一步恶化。在2例患者试图通过微导管/微导丝经闭塞动脉通路时发生术中血管穿孔,尝试进行了补救性胶水栓塞。
破裂血管被有效封堵。然后继续进行支架取栓,实现了脑梗死溶栓分级(TICI)2b级和3级再通。两名患者的神经功能状态均得到改善。
该方法的关键优势在于栓塞破裂血管而不影响后续的机械取栓。我们认为补救性胶水栓塞在处理机械取栓术中血管穿孔并发症方面简单且有效。