Centre for Endocrinology, Diabetology & Osteology, Endocrine Laboratory, Philipp's University and University Hospital Marburg, Marburg, Germany.
German Centre for Endocrine Care, Frankfurt / Main, Germany.
Rev Endocr Metab Disord. 2018 Jun;19(2):133-137. doi: 10.1007/s11154-018-9464-1.
To compare endoscopic ultrasonography (EUS) and magnetic resonance imaging (MRI) in terms of their sensitivities to localize pancreatic neuroendocrine tumors (pNET) preoperatively. Systematic analysis of the literature; sensitivity of EUS and MRI in insulinomas and pancreaticoduodenal NETs in multiple endocrine neoplasia type 1 (MEN1) in series of at least 20 subjects referring to tumors confirmed by surgery and histopathology. Other imaging methods reported were also assessed. Eighteen publications on insulinomas (782 cases) could be analyzed, no study in MEN1 fulfilled the inclusion criteria and compared EUS to MRI. Data quality was moderate: all publications referred to case series. Mean correct detection / localization rates (sensitivity) were calculated: EUS 80%, MRI 66%, computed tomography 63%, angiography 52%, somatostatin receptor scintigraphy 42%, ultrasonography 23%; arterial calcium stimulation with hepatic venous sampling regionalized correctly in 80%. EUS seems to be more sensitive than MRI in localizing pancreatic neuroendocrine tumors. If a specialized endosonographist is available, EUS is the preferable imaging procedure. Otherwise, MRI is a suitable alternative.
比较内镜超声（EUS）和磁共振成像（MRI）在术前定位胰腺神经内分泌肿瘤（pNET）方面的敏感性。对文献进行系统分析；EUS 和 MRI 在至少 20 例手术和组织病理学证实的肿瘤患者的多发性内分泌肿瘤 1 型（MEN1）中的胰岛素瘤和胰十二指肠神经内分泌肿瘤的敏感性。还评估了其他报告的影像学方法。可分析 18 篇关于胰岛素瘤（782 例）的文献，没有研究在 MEN1 中符合纳入标准并将 EUS 与 MRI 进行比较。数据质量为中等：所有出版物均为病例系列。计算了平均正确检测/定位率（敏感性）：EUS 80%，MRI 66%，计算机断层扫描 63%，血管造影 52%，生长抑素受体闪烁扫描 42%，超声 23%；动脉钙刺激肝静脉采样正确定位 80%。EUS 在定位胰腺神经内分泌肿瘤方面似乎比 MRI 更敏感。如果有专门的超声内镜医生，EUS 是首选的影像学检查方法。否则，MRI 是一种合适的替代方法。
