Group Psylux, Neuroacademy & Traumainstitut Luxembourg, Cabinet de Psychologie & de Sciences de la Psychothérapie Khashayar Pazooki, Luxembourg, 53, route d´Arlon, 8211, Mamer, Luxembourg.
Sigmund Freud University Vienna, Vienna, Austria.
Appl Psychophysiol Biofeedback. 2019 Mar;44(1):31-39. doi: 10.1007/s10484-018-9417-1.
Negative symptoms of schizophrenia, like diminished emotional expression and a dearth of self-initiated behavior do not respond reliably to anti-psychotic medication or to conventional psychotherapeutic approaches. Starting from evidence on the probable neural basis of such symptoms and on the effectiveness of neurofeedback with other psychological disorders, the present case study applied 20 sessions of EEG neurofeedback to a 45-year-old female and a 30-year-old male, both diagnosed with severe negative symptoms of schizophrenia. In both cases GAF scores were improved significantly and at the end of treatment, both patients did not meet the diagnostic criteria of negative symptomatology any longer. Symptom reduction went along with an obvious improvement of social, interpersonal, and cognitive abilities according to the clinical impression. Detailed data analysis revealed that these improvements went along with corresponding changes of EEG parameters and with distinct patterns and strategies of change in each of the two individuals. The results suggest that EEG neurofeedback should be examined on a larger scale as it offers a promising alternative to existing treatment approaches for negative symptoms in schizophrenia.
精神分裂症的阴性症状，如情绪表达减弱和自我发起行为减少，对抗精神病药物或传统心理治疗方法的反应并不可靠。从这些症状的可能神经基础的证据以及神经反馈对其他心理障碍的有效性出发，本案例研究对 1 名 45 岁女性和 1 名 30 岁男性进行了 20 次脑电神经反馈治疗，他们均被诊断为严重的精神分裂症阴性症状。在这两种情况下，GAF 评分都有显著改善，在治疗结束时，两名患者均不再符合阴性症状的诊断标准。根据临床印象，症状的减轻伴随着社会、人际关系和认知能力的明显改善。详细的数据分析显示，这些改善伴随着 EEG 参数的相应变化，以及在这两个人中每个人的变化模式和策略都很明显。结果表明，应该在更大范围内检查脑电神经反馈，因为它为治疗精神分裂症阴性症状提供了一种有前途的替代现有治疗方法。
