Abdollahzadeh Baghaei Tannaz, Katebi Katayoun, Jafari Tayebpour Mahsa, Hashemi Mohsen
Department of Orthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
J Dent Res Dent Clin Dent Prospects. 2024 Spring;18(2):152-156. doi: 10.34172/joddd.41128. Epub 2024 Jun 24.
Ulcers caused by mucosal irritation of fixed orthodontic appliances remain an unsolved problem, and more research is needed to improve the pain caused by orthodontic appliances to provide more comfortable treatment for these patients. This study investigated the effect of probiotic Lactogum on pain and ulceration in patients undergoing fixed orthodontic treatment.
In this study, 64 patients over 12 years of age and candidates for fixed orthotic treatment were divided into case and control groups (n=32). The control group received orthodontic waxes, and the case group received the same orthodontic waxes and "Lactogum" probiotic lozenges from the beginning of the treatment. The number of ulcers, the amount of pain, and the location of the ulcer were recorded and compared between the two groups. An independent-sample t-test was used to compare the pain level and number of ulcers between the two groups. A significance level of 0.05 was considered for all tests. SPSS 17 was used for data analysis.
The mean number of ulcers in the case group was significantly lower than the control group (<0.001). The mean pain in the case group was significantly lower than in the control group (<0.001). The most frequent location of ulcers was the buccal mucosa, followed by the labial mucosa.
Lactogum probiotic lozenges can reduce traumatic oral ulcers and pain levels in patients undergoing fixed orthodontic treatment. However, larger clinical trials are encouraged to confirm these findings.
固定正畸矫治器引起的黏膜刺激导致的溃疡仍是一个未解决的问题，需要更多研究来改善正畸矫治器引起的疼痛，为这些患者提供更舒适的治疗。本研究调查了益生菌 Lactogum 对接受固定正畸治疗患者的疼痛和溃疡的影响。
在本研究中，将 64 名 12 岁以上且适合固定正畸治疗的患者分为病例组和对照组（n = 32）。对照组使用正畸蜡，病例组从治疗开始就使用相同的正畸蜡和“Lactogum”益生菌含片。记录并比较两组的溃疡数量、疼痛程度和溃疡位置。使用独立样本 t 检验比较两组之间的疼痛水平和溃疡数量。所有测试的显著性水平均设定为 0.05。使用 SPSS 17 进行数据分析。
病例组的平均溃疡数量显著低于对照组（<0.001）。病例组的平均疼痛程度显著低于对照组（<0.001）。溃疡最常见的位置是颊黏膜，其次是唇黏膜。
Lactogum 益生菌含片可减少接受固定正畸治疗患者的创伤性口腔溃疡和疼痛程度。然而，鼓励进行更大规模的临床试验来证实这些发现。
