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[主动吸烟:一项医院调查中人类非传染性疾病的主要危险因素]

[Active smoking: A major risk factor for human non-communicable diseases in a hospital survey].

作者信息

Ben Ayed H, Ben Hmida M, Ben Jemaa M, Trigui M, Jedidi J, Karray R, Mejdoub Y, Kassis M, Feki H, Yaich S, Damak J

机构信息

Service de médecine communautaire et d'épidémiologie, CHU Hédi-Chaker, Sfax, Tunisie.

Service de médecine communautaire et d'épidémiologie, CHU Hédi-Chaker, Sfax, Tunisie.

出版信息

Rev Mal Respir. 2019 Feb;36(2):171-178. doi: 10.1016/j.rmr.2018.02.011. Epub 2018 Sep 27.

DOI:10.1016/j.rmr.2018.02.011
PMID:30270147
Abstract

INTRODUCTION

Tobacco is the main preventable cause of death worldwide. Our study aimed to determine the role of tobacco in the occurrence of non-communicable diseases (NCDs).

METHODS

We conducted a retrospective study including all NCDs patients during 2015-2016. NCDs include cardiovascular diseases (CVD), chronic respiratory diseases (CRD), cancers (CS) and diabetes mellitus (DM).

RESULTS

We identified 3643 cases of NCDs (43%) among 8478 hospitalizations, all diseases combined. Active smoking was found in 1076 cases (29.5%). Among the NCDs groups, CVD was the most common (65%). Tobacco was significantly associated with CVD (P<0.001), CRD (P=0.002), bronchopulmonary CS (P<0.001), haematological malignancy (P=0.023), and DM (P<0.001). Multivariate analysis performing binary logistic regression revealed that tobacco was an independent factor associated with CVD (OR=2.6, P<0.001), CRD (OR=1.5, P<0.001), bronchopulmonary CS (OR=1.8, P=0.013) and DM (OR=3.6, P<0.001).

CONCLUSION

Active smoking was a major risk factor in the occurrence of NCDs. Thus, smoking cessation represents the cornerstone for preventing the spread of these diseases, especially in countries with limited resources.

摘要

引言

烟草是全球主要的可预防死亡原因。我们的研究旨在确定烟草在非传染性疾病(NCDs)发生中的作用。

方法

我们进行了一项回顾性研究,纳入了2015 - 2016年期间所有的非传染性疾病患者。非传染性疾病包括心血管疾病(CVD)、慢性呼吸道疾病(CRD)、癌症(CS)和糖尿病(DM)。

结果

在8478例住院病例中,我们共识别出3643例非传染性疾病患者(占43%),涵盖所有疾病类型。其中1076例(29.5%)为现吸烟者。在非传染性疾病组中,心血管疾病最为常见(占65%)。烟草与心血管疾病(P<0.001)、慢性呼吸道疾病(P = 0.002)、支气管肺部癌症(P<0.001)、血液系统恶性肿瘤(P = 0.023)和糖尿病(P<0.001)显著相关。进行二元逻辑回归的多变量分析显示,烟草是与心血管疾病(OR = 2.6,P<0.001)、慢性呼吸道疾病(OR = 1.5,P<0.001)、支气管肺部癌症(OR = 1.8,P = 0.013)和糖尿病(OR = 3.6,P<0.001)相关的独立因素。

结论

现吸烟是发生非传染性疾病的主要危险因素。因此,戒烟是预防这些疾病传播的基石,尤其是在资源有限的国家。

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