Ben Ayed Houda, Jedidi Jihène, Yaich Sourour, Mejdoub Yosra, Ben Hmida Mariem, Trigui Maroua, Ben Jemaa Maissa, Karray Raouf, Feki Habib, Kassis Mondher, Damak Jamel
Sante Publique. 2019 May-June;Vol. 31(3):433-441. doi: 10.3917/spub.193.0433.
Non-communicable diseases (NCDs) represent a major public health problem worldwide. Giving their impact on the morbidity and mortality burden, understanding their chronological trends over time is a priority for epidemiological surveillance. We aimed to determine the epidemiological specificities of NCDs and to study their chronological trends over the period 2010-2015.
We retrospectively collected data of hospitalized patients from the regional registry of morbidity and mortality in the Southern University Hospital of Tunisia during the period 2010-2015.
We included 18,081 patients with NCDs aged ≥ 25 years. The distribution of NCDs was characterized by the predominance of cardiovascular disease (CVD) (10,346 cases, 57.2%). Chronological trends analysis of NCDs showed that NCDs remained globally stable between 2010 and 2015. The same result applied to the group of cancers, chronic respiratory diseases and diabetes mellitus. However, CVD increased significantly between 2010 and 2015 (ρ = 0.84; p = 0.036). The proportion of CVD increased significantly among men (ρ = 0.87; p = 0.019) and elderly (ρ = 0.88; p = 0.019). The hospital mortality rate of NCDs increased significantly (ρ = 0.85; p = 0.031), notably for CVDs (ρ = 0.94; p = 0.005).
Chronological trends analysis revealed a significant rise in the morbidity and mortality burden of CVDs during the period 2010-2015. It is imperative, therefore, to strengthen health care for these patients and to introduce the concept of integrated NCDs prevention as an essential component of the health system.
非传染性疾病（NCDs）是全球主要的公共卫生问题。鉴于其对发病率和死亡率负担的影响，了解其随时间的变化趋势是流行病学监测的重点。我们旨在确定非传染性疾病的流行病学特征，并研究2010 - 2015年期间其随时间的变化趋势。
我们回顾性收集了2010 - 2015年期间突尼斯南部大学医院区域发病率和死亡率登记处住院患者的数据。
我们纳入了18081例年龄≥25岁的非传染性疾病患者。非传染性疾病的分布以心血管疾病（CVD）为主（10346例，57.2%）。非传染性疾病的时间趋势分析表明，2010年至2015年期间非传染性疾病总体保持稳定。这一结果同样适用于癌症、慢性呼吸道疾病和糖尿病组。然而，2010年至2015年期间心血管疾病显著增加（ρ = 0.84；p = 0.036）。心血管疾病在男性（ρ = 0.87；p = 0.019）和老年人（ρ = 0.88；p = 0.019）中的比例显著增加。非传染性疾病的医院死亡率显著上升（ρ = 0.85；p = 0.031），尤其是心血管疾病（ρ = 0.94；p = 0.005）。
时间趋势分析显示，2010年至2015年期间心血管疾病的发病率和死亡率负担显著上升。因此必须加强对这些患者的医疗保健，并引入非传染性疾病综合预防概念，将其作为卫生系统的重要组成部分。
