Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyodaku, Tokyo, 102-8554, Japan.
Microwave Science Research Center (MSRC), Sophia University, 7-1 Kioicho, Chiyodaku, Tokyo, 102-8554, Japan.
Chem Rec. 2019 Jan;19(1):118-139. doi: 10.1002/tcr.201800062. Epub 2018 Oct 2.
Several studies have used microwaves as a heat source for carrying out various types of reactions employing circulation reaction vessels. The microwave flow chemical synthesis methodology is most appropriate in the use of microwaves in chemical syntheses. It can attenuate the problem of microwave heating (non-uniform heating and penetration depth) and maximize the benefits (rapid heating and first temperature adjustments). In this brief review, we examine and explain some of the relevant features of microwave heating with applicative examples of the usage of microwave flow chemistry equipment in carrying out organic syntheses, enzymatic reactions, and (not least) nanoparticle syntheses.
已有多项研究采用微波作为热源,通过循环反应容器来进行各种类型的反应。在化学合成中,微波流动化学合成方法是使用微波的最佳方式。它可以减弱微波加热(加热不均匀和穿透深度)的问题,并最大限度地发挥其优势(快速加热和首次温度调整)。在本篇简短的综述中,我们通过应用实例来检查和解释微波加热的一些相关特征,这些实例涉及使用微波流动化学设备进行有机合成、酶反应,以及(尤为重要的)纳米颗粒合成。