Wilkie Gianna L, Taggart Ashley A, Prensner John R, Billett Amy L, Laufer Marc R
Division of Gynecology, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts.
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
J Pediatr Adolesc Gynecol. 2019 Feb;32(1):90-92. doi: 10.1016/j.jpag.2018.09.009. Epub 2018 Sep 29.
Menorrhagia is a common gynecologic complaint among adolescents, which rarely is secondary to malignancy. Burkitt lymphoma can mimic gynecologic malignancy, however it is rarely seen in adolescents. Burkitt lymphoma of the gynecologic tract requires early diagnosis and intervention for optimal outcomes.
We report a case of a 15-year-old adolescent who had multiple admissions for menorrhagia that was thought to be secondary to anovulatory bleeding until pelvic ultrasound revealed a large 8-cm vaginal/cervical mass. Histologic examination of the biopsy specimen revealed Burkitt lymphoma, which was treated with chemotherapy leading to resolution of her menorrhagia.
Burkitt lymphoma presenting as a vaginal/cervical mass is exceedingly rare, especially in the adolescent patient. Burkitt lymphoma is generally highly responsive to chemotherapy, and symptoms rapidly improve after initiation of treatment.
月经过多是青少年常见的妇科主诉，很少继发于恶性肿瘤。伯基特淋巴瘤可酷似妇科恶性肿瘤，但在青少年中罕见。生殖道伯基特淋巴瘤需要早期诊断和干预以获得最佳预后。
我们报告一例15岁青少年，因月经过多多次入院，最初认为是无排卵性出血所致，直到盆腔超声发现一个8厘米大的阴道/宫颈肿物。活检标本的组织学检查显示为伯基特淋巴瘤，经化疗后月经过多症状得到缓解。
表现为阴道/宫颈肿物的伯基特淋巴瘤极为罕见，尤其是在青少年患者中。伯基特淋巴瘤通常对化疗高度敏感，治疗开始后症状迅速改善。
