a Department of Medical Sciences , Uppsala University , Sweden.
Ups J Med Sci. 2019 Jan;124(1):16-20. doi: 10.1080/03009734.2018.1515282. Epub 2018 Oct 3.
The first population-based cohort study in Uppsala with the aim to study cardiovascular disease was initiated in 1970 (ULSAM). This cohort of 2300 middle-aged men has since then been followed in a longitudinal fashion for almost 50 years. This study has been followed by the PIVUS study, investigating 1000 men and women at ages 70, 75, and 80. A very detailed examination has also been performed in 500 subjects aged 50 years, the POEM study. In recent years, a high-throughput study conducted in 13000 subjects has also been performed, named EpiHealth. Uppsala also collects data in 5,000 subjects in the nationwide SCAPIS study. Taken together, these cardiovascular-oriented studies constitute a very rich source for cardiovascular epidemiological research in Uppsala. This review summarizes the design of these studies and highlights some of the important results published based on data from these studies.
乌普萨拉的首个以心血管疾病为研究目标的基于人群的队列研究始于 1970 年（ULSAM）。该队列包括 2300 名中年男性，自那时以来，他们一直进行了近 50 年的纵向随访。该研究之后是 PIVUS 研究，调查了 1000 名年龄在 70、75 和 80 岁的男性和女性。在 500 名年龄在 50 岁的受试者中也进行了非常详细的检查，即 POEM 研究。近年来，还在 13000 名受试者中进行了一项高通量研究，名为 EpiHealth。乌普萨拉还在全国性的 SCAPIS 研究中收集了 5000 名受试者的数据。这些以心血管为导向的研究共同构成了乌普萨拉心血管流行病学研究的丰富资源。这篇综述总结了这些研究的设计，并重点介绍了基于这些研究数据发表的一些重要结果。
