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颈椎经椎间孔硬膜外类固醇注射治疗颈椎间盘突出症所致颈部疼痛的有效性:长期结果

The effectiveness of cervical transforaminal epidural steroid injection for the treatment of neck pain due to cervical disc herniation: long-term results.

作者信息

Kesikburun Serdar, Aras Berke, Kelle Bayram, Yavuz Ferdi, Yaşar Evren, Taşkaynatan Mehmet A

机构信息

Department of Physical Medicine & Rehabilitation, Gulhane School of Medicine, University of Health Science, Ankara 06100, Turkey.

Kastamonu Rehabilitation Centre, Kastamonu 37100, Turkey.

出版信息

Pain Manag. 2018 Sep 1;8(5):321-326. doi: 10.2217/pmt-2018-0002. Epub 2018 Oct 3.

Abstract

AIM

To investigate the long-term effect of fluoroscopy guided cervical transforaminal epidural steroid injection on neck pain radiating to the arm due to cervical disc herniation.

MATERIALS & METHODS: 64 patients (26 women [40.6%], 38 men [59.4%]; mean age, 44.9 ± 12.1 years) who had received fluoroscopy guided cervical transforaminal epidural steroid injection for neck pain due to cervical disc herniation at least 1 year before were included in the study. The effectiveness of transforaminal epidural steroid injection was assessed using data obtained by medical records and a standardized telephone questionnaire. Multiple linear regression analysis was applied to evaluate the factors affecting the pain reduction after injection and the duration of treatment effect.

RESULTS

The mean duration of neck pain symptom was 23.3 ± 23.9 months. Most of the patients received a single injection (50 patients, 78.1%). The mean time since injection at the time of interview was 21.4 ± 9.4 months. There was a significant reduction in mean pain visual analog scale (VAS [10 cm]) score, from 8.6 ± 1.4 at baseline to 3.2 ± 2.5 at check visit two weeks after injection (p < 0.001). 52 patients (81.2%) reported pain relief of more than 50%. The mean duration of treatment effect was 13.3 ± 9.44 months. Greater pain on the VAS was found to predict strongly the higher pain reduction and longer treatment effect (p = 0.042 and 0.011, respectively).

CONCLUSION

The results suggested that cervical transforaminal epidural steroid injections might be an effective treatment for neck back pain radiating to the arm due to cervical disc herniation.

摘要

目的

探讨透视引导下颈椎经椎间孔硬膜外类固醇注射治疗颈椎间盘突出症所致放射至手臂的颈部疼痛的长期疗效。

材料与方法

本研究纳入了64例患者(26例女性[40.6%],38例男性[59.4%];平均年龄44.9±12.1岁),这些患者至少在1年前接受了透视引导下颈椎经椎间孔硬膜外类固醇注射治疗颈椎间盘突出症所致的颈部疼痛。采用病历资料和标准化电话问卷所获数据评估经椎间孔硬膜外类固醇注射的疗效。应用多元线性回归分析评估影响注射后疼痛减轻及治疗效果持续时间的因素。

结果

颈部疼痛症状的平均持续时间为23.3±23.9个月。大多数患者接受了单次注射(50例患者,78.1%)。访谈时距注射的平均时间为21.4±9.4个月。疼痛视觉模拟量表(VAS[10厘米])评分显著降低,从基线时的8.6±1.4降至注射后两周复诊时的3.2±2.5(p<0.001)。52例患者(81.2%)报告疼痛缓解超过50%。治疗效果的平均持续时间为13.3±9.44个月。发现VAS评分越高,疼痛减轻越明显且治疗效果持续时间越长(分别为p=0.042和0.011)。

结论

结果表明,颈椎经椎间孔硬膜外类固醇注射可能是治疗颈椎间盘突出症所致放射至手臂的颈背部疼痛的有效方法。

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