Hedelin H, Grenabo L, Pettersson S
Urol Res. 1986;14(6):305-7. doi: 10.1007/BF00262380.
Previous studies have found that human urine inhibits urease-induced crystallization in synthetic urine. To identify the inhibitory components the effects of chondroitin sulphate, heparin and pyrophosphate on urease-induced crystallization were studied and the inhibitory capacity of human urine collected during and before/after allopurinol treatment compared. None of the substances studied nor allopurinol treatment was found to influence the urease-induced crystallization. These findings do not support the idea that glycosaminoglycans or pyrophosphate are responsible for the inhibitory effect detected in human urine.
先前的研究发现，人尿可抑制合成尿液中脲酶诱导的结晶。为了鉴定抑制成分，研究了硫酸软骨素、肝素和焦磷酸盐对脲酶诱导结晶的影响，并比较了别嘌醇治疗期间及治疗前后收集的人尿的抑制能力。研究的物质和别嘌醇治疗均未发现会影响脲酶诱导的结晶。这些发现不支持糖胺聚糖或焦磷酸盐是人类尿液中检测到的抑制作用的原因这一观点。
