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评估一家三级医院中毒患者的农药中毒模式和结局。

Assessment of pattern and outcomes of pesticides poisoning in a tertiary care hospital.

机构信息

Department of Pharmacy Practice, Maharishi Markandeshwar College of Pharmacy, Mullana (Ambala), India.

出版信息

Trop Med Int Health. 2018 Dec;23(12):1401-1407. doi: 10.1111/tmi.13156. Epub 2018 Oct 23.

Abstract

OBJECTIVES

To assess the socio-demographic profile, pattern and treatment outcomes of pesticides poisoning.

METHODS

A prospective observational study was conducted at the department of emergency medicine of a South Indian tertiary care hospital for 1.5 years to study the pattern and outcomes of poisoning cases due to pesticides. Level of significance (P) <0.05 was considered as statistically significant.

RESULTS

A total of 375 poisoning victims with intentional/accidental exposure to pesticides were followed up and documented. The male-female ratio was 1:0.32; mean age was 31.65 ± 13.10 years. 72% of cases were rural residents. Organophosphorus compounds were the most implicated pesticides. Mean Glasgow Comatose Score (GCS) of the patients was 12.22 ± 3.86. 80.3% of patients recovered while 6.4% died. About 13.3% patients were lost to follow-up as they were discharged against medical advice (DAMA).

CONCLUSION

There was a statistical significance seen in the implication of pesticides for intentional poisoning with age, route of administration, area of residence and occupation of the victims. However, there was a strong association of the outcomes of poisoning with the toxic agent implicated for the poisoning.

摘要

目的

评估农药中毒的社会人口学特征、模式和治疗结果。

方法

在一家印度南部三级护理医院的急诊医学科进行了一项为期 1.5 年的前瞻性观察研究,以研究因农药中毒的病例模式和结果。具有统计学意义的水平(P)<0.05。

结果

共随访和记录了 375 名因故意/意外接触农药而中毒的中毒者。男女比例为 1:0.32;平均年龄为 31.65±13.10 岁。72%的病例为农村居民。有机磷化合物是最易涉及的农药。患者的平均格拉斯哥昏迷评分(GCS)为 12.22±3.86。80.3%的患者康复,6.4%的患者死亡。约 13.3%的患者因出院时未遵医嘱(DAMA)而失去随访。

结论

在受害者的年龄、给药途径、居住地区和职业方面,有意中毒中农药的使用存在统计学意义。然而,中毒的结果与中毒的有毒剂有很强的关联。

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