Jun Seungah, Lee Jung Hee, Gong Han Mi, Choi Seong Hun, Bo Min Hwang, Kang Mi Suk, Lee Geon-Mok, Lee Hyun-Jong, Kim Jae Soo
Department of Acupuncture & Moxibustion medicine, College of Korean medicine, Daegu Haany University, 136, Sincheondong-ro, Suseong-gu, Daegu, 706-828, Korea.
Department of Anatomy and Histology, College of Korean medicine, Daegu Haany University, 136, Sincheondong-ro, Suseong-gu, Daegu, Korea.
J Pharmacopuncture. 2018 Sep;21(3):151-158. doi: 10.3831/KPI.2018.21.018. Epub 2018 Sep 30.
We investigated the efficacy and safety of miniscalpel acupuncture (MA) for knee osteoarthritis (KOA) in an assessor-blinded randomized controlled pilot trial; this would provide information for a large-scale randomized controlled trial.
Participants (n = 24) were recruited and randomly allocated to the MA group (experimental) or acupuncture group (control). The MA group received treatment once a week for 3 weeks (total of 3 treatments), while the acupuncture group received treatment two times per week for 3 weeks (total of 6 treatments). The primary outcome was pain as assessed by a visual analogue scale (VAS). The secondary outcomes (intensity of current pain, stiffness, and physical function) were assessed using the short-form McGill Pain Questionnaire (SF-MPQ) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Assessments were performed at baseline, 1, 2, and 3 during treatment and at week 5 (2 weeks after the end of treatment).
Of the 24 participants, 23 completed the study. Both groups showed significant improvements in VAS, SF-MPQ, and WOMAC. However, there were no significant differences between the MA and acupuncture groups. No serious adverse event occurred and blood test results were within normal limits.
Our results suggest that although both MA and acupuncture provide similar effects with regard to pain control in patients with KOA, MA may be more effective in providing pain relief because the same relief was obtained with fewer treatments. A large-scale clinical study is warranted to further clarify these findings.
我们在一项评估者盲法随机对照试验中研究了小针刀针灸（MA）治疗膝骨关节炎（KOA）的疗效和安全性；这将为大规模随机对照试验提供信息。
招募参与者（n = 24）并随机分配至MA组（实验组）或针灸组（对照组）。MA组每周接受一次治疗，共3周（总计3次治疗），而针灸组每周接受两次治疗，共3周（总计6次治疗）。主要结局指标是通过视觉模拟量表（VAS）评估的疼痛。次要结局指标（当前疼痛强度、僵硬程度和身体功能）使用简式麦吉尔疼痛问卷（SF-MPQ）和西安大略和麦克马斯特大学骨关节炎指数（WOMAC）进行评估。在基线、治疗期间的第1、2和3周以及第5周（治疗结束后2周）进行评估。
24名参与者中，23名完成了研究。两组在VAS、SF-MPQ和WOMAC方面均显示出显著改善。然而，MA组和针灸组之间没有显著差异。未发生严重不良事件，血液检查结果在正常范围内。
我们的结果表明，虽然MA和针灸在控制KOA患者疼痛方面提供了相似的效果，但MA可能在缓解疼痛方面更有效，因为用较少的治疗次数获得了相同的缓解效果。有必要进行大规模临床研究以进一步阐明这些发现。
