Puzikov A M, Lychkova A E
Eksp Klin Gastroenterol. 2016(7):62-5.
The study of mechanisms of regulation of biliary tract motility by divisions of autonomic nervous system (ANS).
Experiments were carried out on rabbits, chinchillas weighing 3.5-4 kg using gentle methods of treatment of experimental animals. Electromotor activity of electromotor (EMA) of the gallbladder and sphincter of Oddi was recorded. Irritation of the nerve produces an electrical pulse duration of 2 ms, the amplitude of 1.5-15 V, frequency of 10 Hz.
The mechanism of vagal inhibition of sphincter of Oddi motility and unidirectional stimulatory influence of ANS divisions on the motility of the gallbladder and sphincter of Oddi was studied. It was established that in the mechanism of vagal inhibition of sphincter of Oddi motility involved intramural adrenergic neurons synaptically connected with preganglionic parasympathetic fibers. At the stimulatory effect of vagus on biliary tract motility serotonergic intramural neurons are involved transmitting excitation to serotonin receptors of effector tissue.
研究自主神经系统（ANS）各分支对胆道运动的调节机制。
采用温和的实验动物处理方法，对体重3.5 - 4千克的家兔、龙猫进行实验。记录胆囊和Oddi括约肌的电运动活动（EMA）。刺激神经产生的电脉冲持续时间为2毫秒，幅度为1.5 - 15伏，频率为10赫兹。
研究了迷走神经对Oddi括约肌运动的抑制机制以及ANS各分支对胆囊和Oddi括约肌运动的单向刺激影响。已确定在迷走神经对Oddi括约肌运动的抑制机制中，涉及与节前副交感纤维突触连接的壁内肾上腺素能神经元。在迷走神经对胆道运动的刺激作用中，血清素能壁内神经元参与将兴奋传递至效应器组织的血清素受体。
