Lopes Ana M, Rouco Carlos, Esteves Pedro J, Abrantes Joana
CIBIO/InBio-UP, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Vairão, Portugal.
Instituto de Ciências Biomédicas Abel Salazar (ICBAS)/Unidade Multidisciplinar de Investigação Biomédica (UMIB), Universidade do Porto, Porto, Portugal.
Arch Virol. 2019 Jan;164(1):279-283. doi: 10.1007/s00705-018-4052-y. Epub 2018 Oct 4.
Rabbit hemorrhagic disease virus (RHDV) is highly lethal to the European rabbit (Oryctolagus cuniculus). It was first reported in 1984 in China, but in 2010, a new variant of the virus was detected (GI.2) in France. Several recombination events with pathogenic and non-pathogenic strains have been described. Here, we report the first sequences of RHDV in Africa, isolated from Moroccan rabbits, and these resemble GI.1b/GI.1b/GI.2 recombinants found in the Iberian Peninsula. Monitoring and characterization of strains from future outbreaks are advised to guarantee the success of current programs on small-rabbit production for poverty alleviation in African countries.
兔出血症病毒(RHDV)对欧洲兔(穴兔)具有高度致死性。该病毒于1984年在中国首次被报道,但在2010年,法国检测到了该病毒的一个新变种(GI.2)。已经描述了该病毒与致病性和非致病性毒株的几次重组事件。在此,我们报告了从摩洛哥兔中分离出的非洲首例RHDV序列,这些序列与在伊比利亚半岛发现的GI.1b/GI.1b/GI.2重组体相似。建议对未来疫情中的毒株进行监测和特征分析,以确保当前非洲国家小型兔养殖扶贫项目的成功。