Department of Pneumology, Faculty of Medicine, University Medical Centre, Freiburg, Germany.
Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
PLoS One. 2018 Oct 4;13(10):e0205308. doi: 10.1371/journal.pone.0205308. eCollection 2018.
Cough is one of the most common symptoms in general and pulmonary medicine with profound negative impact on health-related quality of life (HRQL). The Leicester Cough Questionnaire (LCQ) is a validated HRQL questionnaire, yet a validated German version of the LCQ is not available and it has never been tested in a cohort with sarcoidosis.
To translate the LCQ into German and determine its psychometric properties.
The LCQ was translated in a forward-backward approach. Structured interviews in sarcoidosis patients were performed. Subsequently, sarcoidosis patients were asked to answer the German LCQ and comparative questionnaires. Distribution properties, item difficulty, concurrent validity, Rasch model fit and internal consistency of the German LCQ were determined.
200 patients with sarcoidosis were included. We provide evidence for reliability, unidimensionality and internal consistency. However, only a moderate correlation with general and respiratory-specific HRQL questionnaires, no Rasch model fit could be shown. Skewed responses caused by floor effects were detected.
We demonstrate that the German LCQ is valid and reliable and its psychometric properties fulfil the standards required for its use in clinical settings as well as in interventional trials.
咳嗽是一般医学和肺部医学中最常见的症状之一,对健康相关生活质量(HRQL)有深远的负面影响。莱斯特咳嗽问卷(LCQ)是一种经过验证的 HRQL 问卷,但目前尚没有经过验证的 LCQ 德文版本,而且它从未在结节病患者队列中进行过测试。
将 LCQ 翻译成德文,并确定其心理测量特性。
采用前后向翻译法对 LCQ 进行翻译。对结节病患者进行结构式访谈。随后,要求结节病患者回答德国 LCQ 和比较问卷。确定德国 LCQ 的分布特性、项目难度、同时效度、Rasch 模型拟合度和内部一致性。
共纳入 200 例结节病患者。我们提供了可靠性、单维性和内部一致性的证据。然而,与一般和呼吸特异性 HRQL 问卷的相关性仅为中度,无法显示 Rasch 模型拟合度。检测到由于下限效应导致的偏态反应。
我们证明德国 LCQ 具有有效性和可靠性,其心理测量特性符合在临床环境以及干预试验中使用的标准。