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数学生物学在癌症研究中的范围。

Scope of Mathematical Biology in Cancer Research.

作者信息

Raj A Thirumal, Patil Shankargouda, Sarode Sachin C, Sarode Gargi S, Gadbail Amol R, Gondivkar Shailesh

机构信息

Department of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India, e-mail:

Division of Oral Pathology, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University Jazan, Kingdom of Saudi Arabia.

出版信息

J Contemp Dent Pract. 2018 Sep 1;19(9):1035-1036.

Abstract

Mathematical biology involves the use of mathematical models derived from biological data to predict the course or outcome of a biological event. In oncology, mathematics plays a vital role in determining the tumor behavior and the optimal treatment strategy including the right combination of treatment modality to be used, and the timing and duration of the treatment. The major limiting factor in mathematical oncology is the inability to obtain accurate biological data to formulate appropriate mathematical models. Development of molecular biology has enabled us to overcome these limitations.

摘要

数学生物学涉及使用从生物学数据推导而来的数学模型来预测生物事件的进程或结果。在肿瘤学中,数学在确定肿瘤行为和最佳治疗策略方面发挥着至关重要的作用,包括所用治疗方式的正确组合以及治疗的时间和持续时间。数学肿瘤学的主要限制因素是无法获得准确的生物学数据来构建合适的数学模型。分子生物学的发展使我们能够克服这些限制。

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