Department of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, Iran.
Molecules. 2018 Oct 4;23(10):2532. doi: 10.3390/molecules23102532.
Carbon‒carbon (C‒C) and carbon‒heteroatom (C‒X) bonds that form via transition-metal-catalyzed processes have been extensively used in the organic synthesis and preparation of natural products and important compounds such as heterocycles, biologically active molecules, and dendrimers. Among the most significant catalysts, magnetic nanoparticles-supported palladium complexes are very effective, versatile, and heterogeneous catalysts for a wide range of C‒C and C‒X coupling reactions due to their reusability, thermal stability, and excellent catalytic performance. In this review, recent advances to develop magnetic nanoparticles supported palladium complexes, including their preparation, characterization, catalytic application, and reusability in the formation of both C‒C and C‒X bonds, by authors such as Sonogashira, Heck, Suzuki‒Miyaura, and Stille, and a few examples concerning N-arylation, S-arylation, and C-P coupling reactions are discussed.
通过过渡金属催化过程形成的碳-碳（C-C）和碳-杂原子（C-X）键已广泛应用于有机合成和天然产物以及杂环、生物活性分子和树枝状大分子等重要化合物的制备中。在最有效的催化剂中，磁性纳米粒子负载钯配合物是非常有效的、多功能的和多相催化剂，可用于广泛的 C-C 和 C-X 偶联反应，因为它们具有可重复使用性、热稳定性和优异的催化性能。在这篇综述中，作者讨论了近年来开发磁性纳米粒子负载钯配合物的进展，包括其制备、表征、催化应用以及在 C-C 和 C-X 键形成中的可重复使用性，例如 Sonogashira、Heck、Suzuki-Miyaura 和 Stille 偶联反应，以及一些关于 N-芳基化、S-芳基化和 C-P 偶联反应的例子。
