用身体活动替代久坐时间及其与虚弱状态的关联。
Isotemporal substitution of sedentary time with physical activity and its associations with frailty status.
机构信息
Department of Physical Therapy, School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan,
Department of General Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
出版信息
Clin Interv Aging. 2018 Sep 25;13:1831-1836. doi: 10.2147/CIA.S175666. eCollection 2018.
OBJECTIVES
Recently, isotemporal substitution has been developed to substitute activity time for an equivalent amount of another activity. This study employed this method to demonstrate the effects of replacing sedentary behavior (SB) time with an equivalent amount of light-intensity physical activity (LPA) and moderate-to-vigorous intensity physical activity (MVPA) on the risk for different severities of frailty.
METHODS
A total of 886 older adults (average age 73.6 years, female 70%) participated in this cross-sectional study. Frailty status was assessed according to the cardiovascular health study criteria.
MAIN OUTCOME MEASURES
Wrist-worn accelerometers were used to measure SB, LPA, and MVPA. Isotemporal substitution models were applied to show the estimated effects of substituting 30 min of SB with an equal amount of time spent in LPA or MVPA on the risk for pre-frailty and frailty.
RESULTS
The physical activity level and SB were not associated with the incidence of pre-frailty. However, a 16% (OR: 0.84; 95% CI: 0.78-0.90) and 42% (OR: 0.58; 95% CI: 0.37-0.92) decrease in frailty risk was noted when SB was substituted with LPA and MVPA, respectively, in the crude model. In the adjusted model, the significant effect was sustained for LPA (OR: 0.86; 95% CI: 0.80-0.92) but not for MVPA (OR: 0.74; 95% CI: 0.47-1.17).
CONCLUSIONS
This study indicates that replacing 30 min of SB with an equivalent amount of LPA decreases the risk for frailty in older adults. Moreover, increasing LPA seems more feasible than increasing MVPA in older adults, with substantial benefit.
目的
最近，等时替代法已被开发出来，用于用等量的其他活动替代活动时间。本研究采用这种方法，展示用等量的低强度身体活动（LPA）和中高强度身体活动（MVPA）替代久坐行为（SB）时间对不同严重程度虚弱风险的影响。
方法
共有 886 名年龄在 73.6 岁（女性 70%）的老年人参与了这项横断面研究。根据心血管健康研究标准评估虚弱状况。
主要观察指标
腕戴加速度计用于测量 SB、LPA 和 MVPA。等时替代模型用于显示用 30 分钟 SB 等量时间替代 LPA 或 MVPA 对预虚弱和虚弱风险的估计影响。
结果
身体活动水平和 SB 与预虚弱的发生无关。然而，在粗模型中，用 LPA 和 MVPA 替代 SB 时，虚弱风险分别降低了 16%（OR：0.84；95%CI：0.78-0.90）和 42%（OR：0.58；95%CI：0.37-0.92）。在调整模型中，LPA 的显著效果持续存在（OR：0.86；95%CI：0.80-0.92），而 MVPA 则不然（OR：0.74；95%CI：0.47-1.17）。
结论
本研究表明，用等量的 LPA 替代 30 分钟 SB 可降低老年人虚弱的风险。此外，在老年人中，增加 LPA 似乎比增加 MVPA 更可行，且获益更大。
Zotero 插件