Jiang Cai, Li Yinyan, Guo Miaomiao, Li Xiaomei, Guo Jinhua, Yu Shengxian, Lin Zhonghua
Fujian Provincial Hospital, Fuzhou.
Fujian University of Traditional Chinese Medicine, Fujian, China.
Medicine (Baltimore). 2018 Oct;97(40):e12624. doi: 10.1097/MD.0000000000012624.
Lumbar disc herniation (LDH) is a clinically common degenerative spinal disease that adversely affects patients' quality of life and work ability. Although several articles have reported that acupotomy can improve the clinical symptoms of LDH, the efficiency of acupotomy has not been scientifically or methodically evaluated. The primary objective of this study is to evaluate and synthesize evidence on the effectiveness and safety of acupotomy therapy in patients with LDH.
We plan to search eight English and Chinese electronic databases, including the Web of Science, Cochrane Library, PubMed, EMBASE, SinoMed, Wanfang, China Science and Technology Journal (VIP), and China National Knowledge Infrastructure (CNKI) databases, for potentially eligible studies. Randomized controlled trials (RCTs) on acupotomy treatment in LDH patients will be searched for independently by 2 reviewers in the databases from their inception to August 2018. We will combine data from clinically homogenous studies in a fixed effect meta-analysis using RevManV.5.3.5, and the evidence level will be assessed by using the method for Grading of Recommendations Assessment, Development, and Evaluation (GRADE).
This systematic review and meta-analysis will use high-quality evidence-based medicine to assess the efficacy and safety of acupotomy therapy in LDH.
This study protocol will provide strong evidence to determine whether acupotomy therapy is an effective and safe intervention for patients with LDH.
腰椎间盘突出症（LDH）是一种临床上常见的脊柱退行性疾病，对患者的生活质量和工作能力产生不利影响。尽管有几篇文章报道针刀可以改善LDH的临床症状，但针刀的疗效尚未得到科学或系统的评估。本研究的主要目的是评估和综合针刀疗法治疗LDH患者的有效性和安全性的证据。
我们计划检索八个中英文电子数据库，包括科学引文索引、考克兰图书馆、医学期刊数据库、荷兰医学文摘数据库、中国生物医学文献数据库、万方数据库、维普资讯网和中国知网数据库，以查找可能符合条件的研究。两名综述员将独立在数据库中检索自起始至2018年8月关于针刀治疗LDH患者的随机对照试验（RCT）。我们将使用RevManV.5.3.5对临床同质研究的数据进行固定效应荟萃分析，并使用推荐分级的评估、制定和评价（GRADE）方法评估证据水平。
本系统评价和荟萃分析将使用高质量的循证医学来评估针刀疗法治疗LDH的疗效和安全性。
本研究方案将为确定针刀疗法是否是治疗LDH患者的有效和安全干预措施提供有力证据。
