Carbotta Giuseppe, Panebianco Annunziata, Laforgia Rita, Pascazio Bianca, Balducci Giovanni, Bianchi Francesco Paolo, Tafuri Silvio, Palasciano Nicola
General Surgery Unit "V. Bonomo", Department of Emergency and Transplantation of Organs, University of Bari, P.zza G. Cesare 11, 70124, Bari, Italy.
Department of Biomedical Sciences and Human Oncology, University of Bari, P.zza G. Cesare 11, 70124, Bari, Italy.
Ann Med Surg (Lond). 2018 Sep 22;35:59-63. doi: 10.1016/j.amsu.2018.09.015. eCollection 2018 Nov.
The gold standard treatment of symptomatic cholelithiasis is videolaparoscopic cholecystectomy (VLC). The aim of this study is to produce a predictive clinical ultrasound (US) score for difficult VLC to reduce the rate of conversion to open cholecystectomy surgery and intra and/or post-operative complications.
In this prospective study carried out in 2017 we enrolled 135 patients (pts) who underwent VLC in our General Surgery Unit. A specific pre-operative abdominal ultrasound scan was performed to assess gallbladder characteristics for each patient. All US and patients' characteristics were recorded in a standard form in order to obtain a preoperative score and were then added to the intra-operative variables.
The analysis revealed a statistical significance between post-operative characteristics and parietal thickness, adhesions, stratifications and volume of gallstones. Comparing the degree of difficulty VLC assessed in the pre-operative stage to the intraoperative score, the sensitivity of the preoperative US scan test is 91.8% while the specificity is 76.7%.
The variables which proved statistically significant in predicting a difficult cholecystectomy were: age, parietal thickness >3 mm, adhesions, stratifications, gallstones >2 cm and fixed gallstones. We have definitively defined a predictive score for difficult VLC for which a VLC is to be considered potentially difficult whenever it presents a pre-operative score equal or greater than 4 (and a "easy" one with a pre-operative score less than 4). These findings may prove helpful in further reducing the conversion rate and the rate of intra- and/or post-operative complications.
有症状胆结石的金标准治疗方法是视频腹腔镜胆囊切除术(VLC)。本研究的目的是制定一个针对困难VLC的预测性临床超声(US)评分,以降低转为开腹胆囊切除术的比率以及术中及/或术后并发症的发生率。
在2017年进行的这项前瞻性研究中,我们纳入了135例在我们普通外科接受VLC的患者。对每位患者进行了特定的术前腹部超声扫描,以评估胆囊特征。所有超声和患者特征均以标准表格记录,以获得术前评分,然后添加到术中变量中。
分析显示术后特征与胆囊壁厚度、粘连、分层及胆结石体积之间存在统计学意义。将术前评估的VLC难度程度与术中评分进行比较,术前超声扫描测试的敏感性为91.8%,特异性为76.7%。
在预测困难胆囊切除术中具有统计学意义的变量为:年龄、胆囊壁厚度>3mm、粘连、分层、胆结石>2cm以及固定性胆结石。我们最终确定了一个针对困难VLC的预测评分,当术前评分等于或大于4时,VLC应被视为潜在困难(术前评分小于4则为“容易”)。这些发现可能有助于进一步降低转化率以及术中及/或术后并发症的发生率。