Veterinary Emergency Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, South Korea.
Vet Med Sci. 2024 Jul;10(4):e1508. doi: 10.1002/vms3.1508.
A 6-month-old intact female mixed-breed kitten presented with severe exophthalmos of the left eye. Periocular lesions, including subconjunctival haemorrhage, third eyelid protrusion, and left eyelid oedema, were detected in the absence of globe retropulsion. The left intraocular pressure was increased, and ocular ultrasonography revealed ipsilateral retrobulbar fluid. Coagulation panels were markedly prolonged and severe anaemia was detected. Ultrasound-guided retrobulbar centesis performed to decrease intraocular pressure yielded blood. Based on the history and clinical findings, anticoagulant rodenticide intoxication was suspected. Treatment included partial tarsorrhaphy and the administration of topical antibiotics, artificial tears, and vitamin K. Fresh whole blood and fresh frozen plasma were transfused for supportive therapy. Coagulation parameters improved after 7 days of hospitalisation. The periocular lesions resolved within 14 days, despite persistent optic nerve damage and blindness. This case report raises the possibility that anticoagulant rodenticide toxicity may result in retrobulbar haemorrhage in the absence of other typical cavitary bleeding. Although uncommon, anticoagulant rodenticide toxicity should be considered in cats with retrobulbar haemorrhage.
一只 6 个月大的未绝育雌性混血猫，左眼出现严重眼球突出。在没有眼球后退的情况下，发现了眼周病变，包括结膜下出血、第三眼睑突出和左眼眼睑水肿。左眼眼压升高，眼部超声显示同侧球后积液。凝血酶原时间明显延长，发现严重贫血。为降低眼压进行了超声引导下的球后穿刺，抽出了血液。根据病史和临床发现，怀疑是抗凝灭鼠剂中毒。治疗包括部分睑缘缝合术以及局部使用抗生素、人工泪液和维生素 K。为支持治疗输注了新鲜全血和新鲜冷冻血浆。住院 7 天后，凝血参数得到改善。尽管视神经损伤和失明持续存在，但眼周病变在 14 天内消退。本病例报告提示，在没有其他典型空洞性出血的情况下，抗凝灭鼠剂中毒也可能导致球后出血。尽管不常见，但对于有球后出血的猫，应考虑抗凝灭鼠剂中毒的可能性。
