Hospital for Special Surgery, New York, USA.
Bone Joint J. 2018 Oct;100-B(10):1330-1335. doi: 10.1302/0301-620X.100B10.BJJ-2018-0061.R2.
The aim of this study was to evaluate the surface damage, the density of crosslinking, and oxidation in retrieved antioxidant-stabilized highly crosslinked polyethylene (A-XLPE) tibial inserts from total knee arthroplasty (TKA), and to compare the results with a matched cohort of standard remelted highly crosslinked polyethylene (XLPE) inserts.
A total of 19 A-XLPE tibial inserts were retrieved during revision TKA and matched to 18 retrieved XLPE inserts according to the demographics of the patients, with a mean length of implantation of 15 months (1 to 42). The percentage areas of PE damage on the articular surfaces and the modes of damage were measured. The density of crosslinking of the PE and oxidation were measured at loaded and unloaded regions on these surfaces.
A-XLPE inserts had higher rates of burnishing and lower rates of pitting and scratching compared with XLPE. There were no differences in the density of crosslinking at loaded and unloaded regions. A-XLPE showed higher oxidation indices in the unloaded surface region compared with XLPE. There were no differences in the levels of oxidation in the loaded regions.
Retrieval analysis of A-XLPE did not reflect a clinically relevant difference in surface damage, density of crosslinking, or oxidation compared with XLPE tibial inserts at short-term evaluation. Cite this article: Bone Joint J 2018;100-B:1330-5.
本研究旨在评估从全膝关节置换术中取出的抗氧化稳定型高交联聚乙烯（A-XLPE）胫骨衬垫的表面损伤、交联密度和氧化情况，并与匹配的标准重熔高交联聚乙烯（XLPE）衬垫的结果进行比较。
共从翻修 TKA 中取出 19 个 A-XLPE 胫骨衬垫，并根据患者的人口统计学资料与 18 个取出的 XLPE 衬垫相匹配，植入平均时间为 15 个月（1 至 42 个月）。测量关节表面上 PE 损伤的百分比面积和损伤模式。测量这些表面加载和未加载区域的 PE 交联密度和氧化程度。
与 XLPE 相比，A-XLPE 衬垫的抛光率更高，点蚀和划伤率更低。在加载和未加载区域，交联密度无差异。A-XLPE 在未加载表面区域的氧化指数高于 XLPE。在加载区域，氧化水平无差异。
短期评估结果显示，与 XLPE 胫骨衬垫相比，A-XLPE 的表面损伤、交联密度或氧化程度没有明显的临床差异。
