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在泰国北部,将伯克霍尔德菌误鉴定为不动杆菌属。

Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand.

机构信息

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

出版信息

Trans R Soc Trop Med Hyg. 2019 Jan 1;113(1):48-51. doi: 10.1093/trstmh/try108.

DOI:10.1093/trstmh/try108
PMID:30295891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6314150/
Abstract

BACKGROUND

Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic throughout the tropics.

METHODS

A study of reported Acinetobacter spp. bacteraemia was performed at Chiang Rai provincial hospital from 2014 to 2015. Isolates were collected and tested for confirmation.

RESULTS

A total of 419 putative Acinetobacter spp. isolates from 412 patients were re-identified and 5/419 (1.2%) were identified as B. pseudomallei. Four of the five patients with melioidosis died. An estimated 88/419 (21%) isolates were correctly identified as Acinetobacter spp.

CONCLUSIONS

Misidentification of Acinetobacter spp. as B. pseudomallei or other bacteria is not uncommon and programmes to address these shortfalls are urgently required.

摘要

背景

类鼻疽伯克霍尔德菌是类鼻疽病的病原体,该病在整个热带地区流行。

方法

在 2014 年至 2015 年,对清莱省医院报告的不动杆菌属菌血症进行了一项研究。收集并测试了分离物以进行确认。

结果

从 412 名患者中重新鉴定了总共 419 个疑似不动杆菌属分离物,其中 5/419(1.2%)被鉴定为类鼻疽伯克霍尔德菌。5 名类鼻疽病患者中有 4 人死亡。估计有 88/419(21%)的分离物被正确鉴定为不动杆菌属。

结论

不动杆菌属被错误鉴定为类鼻疽伯克霍尔德菌或其他细菌的情况并不少见,迫切需要制定解决这些缺陷的方案。

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