Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States; Sinai Health System, Toronto, ON, Canada; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, United States; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
J Crit Care. 2018 Dec;48:352-356. doi: 10.1016/j.jcrc.2018.09.034. Epub 2018 Oct 1.
To determine how patients perceive their quality of life (QOL) six months following critical illness and to measure clinicians' discriminative accuracy of predicting this outcome.
This prospective cohort study of intensive care unit (ICU) survivors asked patients to report their QOL strictly at six months compared to one month before their critical illness as better, the same, or worse. ICU physicians and nurses made six-month QOL predictions for these patients.
Of 162 critical illness survivors, 33% (n = 53) of patients reported six-month QOL as better, 33% (n = 54) the same, and 34% (n = 55) worse. Abnormal cognition and inability to return to primary pastime or original place of residence (p < .05 for all) were associated with worse self-reported QOL at six months in multivariable regression. Predictions of patient perceptions of QOL at six months were pessimistic and had low discriminative accuracy for both physicians (sensitivity 56%, specificity 53%) and nurses (sensitivity 49%, specificity 57%).
Among survivors of critical illness, one-third each reported their six-month post-ICU QOL as better, the same, or worse. Self-reported six-month QOL was associated with six-month function. ICU clinicians should use caution in predicting self-reported QOL, as discriminative accuracy was poor in this cohort.
确定患者在重症疾病后六个月如何感知其生活质量(QOL),并衡量临床医生预测该结果的判别准确性。
这项针对重症监护病房(ICU)幸存者的前瞻性队列研究要求患者在与疾病发生前一个月相比,严格在六个月时报告其 QOL 是否更好、相同或更差。ICU 医生和护士对这些患者做出了六个月 QOL 的预测。
在 162 名重症疾病幸存者中,有 33%(n=53)的患者报告六个月 QOL 更好,33%(n=54)相同,34%(n=55)更差。异常认知和无法恢复主要业余爱好或原始居住地(所有 p<0.05)与多变量回归中六个月时自我报告 QOL 较差相关。对于医生(敏感度 56%,特异性 53%)和护士(敏感度 49%,特异性 57%)来说,对患者六个月 QOL 感知的预测均较为悲观,且具有较低的判别准确性。
在重症疾病幸存者中,各有三分之一的患者报告其六个月后 ICU 生活质量更好、相同或更差。自我报告的六个月 QOL 与六个月时的功能相关。ICU 临床医生在预测自我报告的 QOL 时应谨慎,因为在该队列中判别准确性较差。