National Engineering Laboratory for Efficient Utilization of Soil and Fertilizer Resources, College of Resources and Environment, Shandong Agricultural University, Taian 271018, China; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Post Office Box 2871, Beijing 100085, China.
School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Sci Total Environ. 2019 Feb 10;650(Pt 2):2697-2704. doi: 10.1016/j.scitotenv.2018.10.006. Epub 2018 Oct 2.
In this study, eggs from free-range and barn chickens in farms around a fluorochemical facility were collected to assess the distribution profiles of perfluoroalkyl acids (PFAAs), including isomers of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and perfluorohexane sulfonate (PFHxS), in egg yolk and albumen. The results revealed that the concentrations of PFAAs in yolks were significantly higher than those in albumen. All 17 PFAAs examined could be detected in yolks, showing decreasing concentrations with increasing distance from the fluorochemical facility. The three predominant compounds in yolks were perfluorobutanoic acid (PFBA, mean concentration 81.4 ng/g ww), PFOS (28.0 ng/g ww), and PFOA (4.83 ng/g ww), and this result is consistent with the product structure of the facility. Moreover, n-PFOA, n-PFOS, and n-PFHxS were the dominant contaminants in yolk, with mean concentrations of 4.75, 25.7, and 4.29 ng/g ww, respectively. In albumen, PFBA was still the predominant PFAA congener (mean concentration = 3.93 ng/g ww), followed by PFOA. Docking analysis indicated that the PFAAs presented higher binding abilities with the low density lipoprotein, high density lipoprotein, and vitellin proteins in yolk than that with ovalbumin albumen proteins, which might be the main factor influencing the possible difference in distributions of PFAAs in yolk and albumen.
在这项研究中，收集了来自农场中自由放养和笼养鸡的鸡蛋，以评估全氟烷基酸 (PFAAs)，包括全氟辛烷磺酸 (PFOS)、全氟辛酸 (PFOA) 和全氟己烷磺酸 (PFHxS) 的异构体，在蛋黄和蛋清中的分布情况。结果表明，PFAAs 在蛋黄中的浓度明显高于蛋清。在蛋黄中可以检测到所有 17 种 PFAAs，它们的浓度随着与氟化学设施距离的增加而降低。蛋黄中主要的三种化合物是全氟丁烷酸 (PFBA，平均浓度为 81.4ng/g 湿重)、PFOS（28.0ng/g 湿重）和 PFOA（4.83ng/g 湿重），这一结果与设施的产品结构一致。此外，n-PFOA、n-PFOS 和 n-PFHxS 是蛋黄中的主要污染物，平均浓度分别为 4.75、25.7 和 4.29ng/g 湿重。在蛋清中，PFBA 仍然是主要的 PFAAs 同系物（平均浓度为 3.93ng/g 湿重），其次是 PFOA。对接分析表明，PFAAs 与蛋黄中的低密度脂蛋白、高密度脂蛋白和卵黄蛋白的结合能力高于与卵清蛋白的结合能力，这可能是影响 PFAAs 在蛋黄和蛋清中分布差异的主要因素。
