School of Behavioural Sciences, Tel Aviv-Jaffa Academic College, Jaffa, Israel.
Institute of Rheumatology, Tel Aviv Sourasky Medical Center, Israel.
Clin Exp Rheumatol. 2019 Jan-Feb;37 Suppl 116(1):51-57. Epub 2018 Sep 20.
The current provisional diagnostic criteria for the fibromyalgia syndrome (FM) include a cognitive index score (SSS-Cog), which constitutes a part of the Symptom Severity Scale (SSS). The current study aimed at assessing the validity of the cognitive index score, by comparing this subjective measure of cognitive impairment with an objective measure of cognitive functioning, collected through comprehensive computerised cognitive testing and assessment.
50 FM patients underwent a computerised cognitive assessment battery, including testing in domains of memory, executive function, attention and information processing speed (NeuroTraxCorp.). Age and education standardised scores were computed. FM symptoms were assessed by the Fibromyalgia Impact Questionnaire (FIQ), Widespread Pain Index (WPI) and Symptom Severity Scale (SSS), a Visual Analog Scale (VAS) of clinical pain and the Beck Depression inventory (BDI-II).
The index score for subjective assessment of cognitive decline (SSS-Cog) was not correlated with any of the objective cognitive measures. However, a positive correlation was found between the SSS-Cog and the FIQ, the WPI and the VAS measures, all reflecting subjective overall functional ability.
No significant relationship was found between FM patients' subjective appraisal of cognitive deficit and objective cognitive scores on all computerised subtests. However, subjective appraisal of cognitive impairment was found to be strongly and significantly related to patients' functional ability. Therefore, we suggest reconsidering the definition of this index score (SSS-Cog) and propose developing novel and more accurately defined tools in order to measure cognitive impairment in FM patients, for both diagnostic and epidemiological purposes.
纤维肌痛综合征（FM）的现行暂定诊断标准包括认知指数评分（SSS-Cog），它是症状严重程度评分（SSS）的一部分。本研究旨在通过将认知障碍的主观测量与通过全面计算机认知测试和评估收集的认知功能的客观测量进行比较，来评估认知指数评分的有效性。
50 名 FM 患者接受了计算机认知评估测试，包括记忆、执行功能、注意力和信息处理速度测试（NeuroTraxCorp.）。计算了年龄和教育标准化分数。通过纤维肌痛影响问卷（FIQ）、广泛性疼痛指数（WPI）和症状严重程度评分（SSS）、临床疼痛视觉模拟评分（VAS）和贝克抑郁量表（BDI-II）评估 FM 症状。
主观认知下降评估的指数评分（SSS-Cog）与任何客观认知测量均无相关性。然而，SSS-Cog 与 FIQ、WPI 和 VAS 测量值之间存在正相关，所有这些都反映了主观整体功能能力。
在所有计算机子测试中，FM 患者对认知缺陷的主观评估与客观认知评分之间未发现显著关系。然而，主观认知障碍评估与患者的功能能力密切相关。因此，我们建议重新考虑该指数评分（SSS-Cog）的定义，并提出开发新的、更准确定义的工具，以便为诊断和流行病学目的测量 FM 患者的认知障碍。
