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中国中部河南省的儿科脑瘫患病率及高危因素。

Paediatric cerebral palsy prevalence and high-risk factors in Henan province, Central China.

机构信息

.Department of Rehabilitation, the First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, China.

出版信息

J Rehabil Med. 2019 Jan 1;51(1):47-53. doi: 10.2340/16501977-2486.

DOI:10.2340/16501977-2486
PMID:30299526
Abstract

OBJECTIVE

To evaluate the prevalence of, and risk factors for, cerebral palsy in Henan province, China.

METHODS

The prevalence of cerebral palsy in children aged 0-6 years between September 2011 and September 2012 was investigated using a stratified-clustered-random sampling method. An age-, sex- , and residence-matched control group of typically developing children was recruited. Univariate analysis and multinomial logistic regression analysis were used to identify risk factors associated with cerebral palsy.

RESULTS

The prevalence of cerebral palsy in Henan province was 2.37 per 1,000 live births. Risk factors included: moving into a newly painted room; complicating maternal diseases (infection, heart disease, hypertension, anaemia, diabetes, kidney disease) during pregnancy; high gravidity (> 3); foetal asphyxia; low birth-weight (< 2,500 g); and hypoxic-ischaemic encephalopathy.

CONCLUSION

The prevalence of cerebral palsy in Henan province was 2.37 per 1,000 live births. Parents and clinicians should be aware of the risk factors for cerebral palsy.

摘要

目的

评估中国河南省脑瘫的患病率及相关危险因素。

方法

采用分层整群随机抽样方法,于 2011 年 9 月至 2012 年 9 月调查了 0-6 岁儿童脑瘫的患病率。同时招募了一组年龄、性别和居住地相匹配的正常发育儿童作为对照组。采用单因素分析和多变量逻辑回归分析来识别与脑瘫相关的危险因素。

结果

河南省脑瘫患病率为 2.37/1000 活产儿。危险因素包括:搬进新粉刷的房间;孕期合并母亲疾病(感染、心脏病、高血压、贫血、糖尿病、肾病);多胎妊娠(>3 胎);胎儿窒息;低出生体重(<2500g);和缺氧缺血性脑病。

结论

河南省脑瘫的患病率为 2.37/1000 活产儿。家长和临床医生应了解脑瘫的危险因素。

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