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哺乳对产妇高血压的影响:系统评价。

Effect of Lactation on Maternal Hypertension: A Systematic Review.

机构信息

1 Division of General Internal Medicine, Department of Medicine, Montefiore Hospital , Pittsburgh, Pennsylvania.

2 Division of General Internal Medicine, Department of Medicine, University of California Davis Medical Center , Sacramento, California.

出版信息

Breastfeed Med. 2018 Nov;13(9):578-588. doi: 10.1089/bfm.2018.0108. Epub 2018 Oct 6.

Abstract

INTRODUCTION

Hypertension is relatively common in pregnancy, and pregnancy may unmask hypertension among women who are predisposed to it. Lactation may be a means through which to mitigate pregnancy-related vascular risk. The impact of lactation on maternal blood pressure, and the duration of any effect, remains unclear. This study aimed at systematically reviewing the literature evaluating the impact of lactation on the development of hypertension.

MATERIALS AND METHODS

We searched PubMed, including EMBASE and MEDLINE, for studies that reported on the association between breastfeeding and maternal risk of hypertension that were published in a peer-reviewed source. The quality of the studies included was assessed by using the Newcastle-Ottawa Scale.

RESULTS

Nineteen studies met all inclusion criteria for this review. Of the four studies with short-term follow-up, 50% showed a protective association. The fifteen studies with longer-term follow-up were stratified by outcome assessed. Sixty-seven percent of the studies that evaluated for elevated blood pressure and 100% of the studies evaluating for an outcome of hypertension showed a protective association. The minimum duration of lactation associated with a benefit was 1 month. This association was demonstrated in follow-up periods as long as two to three decades. Studies that showed a protective association had overall higher quality ratings.

DISCUSSION

Lactation is associated with a beneficial effect on maternal blood pressure that persists for decades. These results add to the growing body of literature demonstrating the protective association of lactation on maternal cardiovascular risk. Providers may incorporate the decreased risk of hypertension into their counseling on the maternal benefits of lactation.

摘要

简介

高血压在妊娠中较为常见,妊娠可能会使原本易患高血压的女性暴露出高血压。哺乳可能是减轻妊娠相关血管风险的一种方式。哺乳对产妇血压的影响及其持续时间尚不清楚。本研究旨在系统地回顾评估哺乳对高血压发展影响的文献。

材料与方法

我们在同行评审来源的出版物中搜索了评估母乳喂养与产妇高血压风险之间关联的文献,检索了 PubMed,包括 EMBASE 和 MEDLINE。使用纽卡斯尔-渥太华量表评估纳入研究的质量。

结果

19 项研究符合本综述的所有纳入标准。在四项短期随访的研究中,有 50%显示出保护关联。对评估高血压和高血压结局的 15 项长期随访研究进行分层。评估血压升高的研究中有 67%,评估高血压结局的研究中有 100%显示出保护关联。与益处相关的最小哺乳持续时间为 1 个月。这种关联在长达两到三十年的随访期间都有体现。显示出保护关联的研究总体质量评分更高。

讨论

哺乳与产妇血压的有益影响相关,这种影响可持续数十年。这些结果增加了越来越多的文献,证明了哺乳对产妇心血管风险的保护关联。提供者可以将高血压风险降低纳入其关于哺乳对产妇益处的咨询中。

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