Debonera Fotini, Nasta Sunita, Martinez-Lage Maria, Schuster Stephen J, Tsai Donald E
Abramson Cancer Center, Hospital of the University of Pennsylvania, 12 South PCAM, 3400 Civic Center Blvd, PA 19104, USA.
Int J Hematol Oncol. 2017 Nov;6(3):69-73. doi: 10.2217/ijh-2017-0009. Epub 2017 Nov 20.
There is no consensus on the optimal therapy for primary CNS lymphoma. Conventional treatment modalities include chemotherapy and radiation therapy, which carry significant risks of morbidity and mortality. In systemic lymphomas, there are situations where non-Hodgkin lymphomas have resolved spontaneously. We now report the case of a nonimmunocompromised patient with primary CNS lymphoma who underwent a spontaneous remission with a durable response. This case suggests that not all patients with primary CNS lymphomas require aggressive treatment with chemotherapy and radiation therapy.
对于原发性中枢神经系统淋巴瘤的最佳治疗方法尚无共识。传统的治疗方式包括化疗和放疗，这两种治疗方式都有显著的发病和死亡风险。在系统性淋巴瘤中，存在非霍奇金淋巴瘤自发缓解的情况。我们现在报告一例非免疫功能低下的原发性中枢神经系统淋巴瘤患者，该患者实现了自发缓解且缓解期持久。该病例表明，并非所有原发性中枢神经系统淋巴瘤患者都需要接受化疗和放疗的积极治疗。
