Centre of Biotechnology, Nehru Science Complex, University of Allahabad, Allahabad, 211002, India.
National Institute for Research in Environmental Health (NIREH), ICMR, Kamla Nehru Hospital Building, Bhopal, India.
Cell Tissue Res. 2018 Dec;374(3):427-438. doi: 10.1007/s00441-018-2928-5. Epub 2018 Oct 9.
Nanomedicine is the spin-off of modern medicine and nanotechnology and aims to prevent and treat diseases using nanoscale materials such as biocompatible nanoparticles and nanorobots. Targeted cellular and tissue-specific clinical applications with maximal therapeutic effects and insignificant side effects could be achieved by the pursuit of nanotechnology in medicine and healthcare regimen. The majority of conventional cancer therapies eliminate the cells of the tumor but not the cancer stem cells (CSCs). Conversely, the use of nanotechnology in CSC-based therapies is an emerging field of biomedical sciences. This article summarizes the recent trends and application of nanomedicine especially in CSC therapy along with its limitations.
纳米医学是现代医学和纳米技术的分支，旨在利用纳米级材料（如生物相容性纳米粒子和纳米机器人）预防和治疗疾病。通过在医学和医疗方案中追求纳米技术，可以实现针对细胞和组织的靶向临床应用，以达到最大的治疗效果和最小的副作用。大多数传统的癌症疗法可以消除肿瘤细胞，但不能消除癌症干细胞（CSCs）。相反，纳米技术在基于 CSC 的治疗中的应用是生物医学科学的一个新兴领域。本文总结了纳米医学的最新趋势和应用，特别是在 CSC 治疗方面，以及其局限性。
