Department of Regenerative Oral Surgery, Institute of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan.
Center of Oral and Maxillofacial Implants, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan.
Clin Oral Investig. 2019 May;23(5):2413-2419. doi: 10.1007/s00784-018-2705-6. Epub 2018 Oct 9.
The aim of this study was to assess the effectiveness of a hydroxyapatite/collagen composite material (HAp/Col) for preservation of alveolar bone after tooth extraction.
HAp/Col was applied to the alveolus bone ridge preservation after tooth extraction, because of subsequent dental implant placement in 35 regions of 24 patients (mean age, 59.3 years; range, 25-81 years). Cone beam computed tomography was used to assess changes in alveolar bone at the extraction site before and at 3 months (mean, 13.7 weeks; range, 10-17 weeks) after tooth extraction. Changes in height and width of the alveolar bone were measured to evaluate bone reduction after surgery. Bone biopsy was performed at 11 regions of dental implant placement to observe bone regeneration and remaining material in the extraction socket.
The alveolar bone height was decreased by 0.00 ± 2.44 mm at the buccal side and 0.35 ± 1.73 mm at the lingual side, while the width was decreased by 1.02 ± 1.64 mm at 3 months after surgery. The middle of the socket floor was elevated by 5.71 ± 3.45 mm at 3 months after surgery. Bone biopsy specimens revealed no remaining implanted material, and approximately 49.79 ± 14.41% of the specimens were occupied by bone tissue.
According to the result of this study, HAp/Col is a reliable material to presearve alveolar bone after tooth extraction.
HAp/Col contributes dental implant treatment due to maintain the alveolar bone after tooth extraction.
本研究旨在评估羟基磷灰石/胶原复合材料(HAp/Col)在拔牙后牙槽骨保存中的有效性。
将 HAp/Col 应用于拔牙后牙槽嵴保存,因为随后在 24 名患者的 35 个区域(平均年龄 59.3 岁;范围 25-81 岁)中进行牙种植体植入。使用锥形束计算机断层扫描(CBCT)在拔牙前和拔牙后 3 个月(平均 13.7 周;范围 10-17 周)评估拔牙部位牙槽骨的变化。测量牙槽骨高度和宽度的变化,以评估手术后的骨量减少。在 11 个牙种植体植入部位进行骨活检,观察骨再生和拔牙窝内剩余材料。
牙槽骨颊侧高度减少 0.00±2.44mm,舌侧高度减少 0.35±1.73mm,术后 3 个月宽度减少 1.02±1.64mm。牙槽窝底部中间在术后 3 个月升高了 5.71±3.45mm。骨活检标本未见残留植入材料,约 49.79±14.41%的标本为骨组织。
根据本研究结果,HAp/Col 是一种可靠的拔牙后牙槽骨保存材料。
HAp/Col 有助于牙种植治疗,因为它可以保持拔牙后的牙槽骨。