韩国 1 型糖尿病患者中成年人病例比例高且代谢综合征患病率高：一项全国性研究。
High Proportion of Adult Cases and Prevalence of Metabolic Syndrome in Type 1 Diabetes Mellitus Population in Korea: A Nationwide Study.
机构信息
Division of Endocrinology and Metabolism, Department of Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
出版信息
Diabetes Metab J. 2019 Feb;43(1):76-89. doi: 10.4093/dmj.2018.0048. Epub 2018 Aug 22.
BACKGROUND
The prevalence and incidence of type 1 diabetes mellitus (T1DM) in all age groups and the prevalence of metabolic syndrome in patients with T1DM in Korea were estimated.
METHODS
The incidence and prevalence of T1DM between 2007 and 2013 were calculated using the Korean National Health Insurance Service (NHIS) datasets of claims. Clinical characteristics and prevalence of metabolic syndrome in individuals with T1DM between 2009 and 2013 were determined using the database of NHIS preventive health checkups.
RESULTS
The prevalence of T1DM in Korea between 2007 and 2013 was 0.041% to 0.047%. The annual incidence rate of T1DM in Korea in 2007 to 2013 was 2.73 to 5.02/100,000 people. Although the incidence rate of typical T1DM was highest in teenagers, it remained steady in adults over 30 years of age. In contrast, the incidence rate of atypical T1DM in 2013 was higher in people aged 40 years or older than in younger age groups. Age- and sex-adjusted prevalence of metabolic syndrome in patients with T1DM was 51.65% to 55.06% between 2009 and 2013.
CONCLUSION
T1DM may be more common in Korean adults than previously believed. Metabolic syndrome may be a frequent finding in individuals with T1DM in Korea.
背景
本研究旨在评估韩国各年龄段 1 型糖尿病（T1DM）的患病率和发病率，以及 T1DM 患者代谢综合征的患病率。
方法
通过韩国国民健康保险服务（NHIS）理赔数据库，计算了 2007 年至 2013 年 T1DM 的发病率和患病率。通过 NHIS 预防保健数据库，确定了 2009 年至 2013 年 T1DM 患者的临床特征和代谢综合征的患病率。
结果
2007 年至 2013 年，韩国 T1DM 的患病率为 0.041%至 0.047%。2007 年至 2013 年，韩国 T1DM 的年发病率为 2.73 至 5.02/10 万。虽然青少年中典型 T1DM 的发病率最高，但 30 岁以上成年人的发病率保持稳定。相比之下，2013 年非典型 T1DM 的发病率在 40 岁及以上人群中高于其他年龄组。2009 年至 2013 年，年龄和性别调整后 T1DM 患者代谢综合征的患病率为 51.65%至 55.06%。
结论
与以往认为的相比，T1DM 在韩国成年人中可能更为常见。代谢综合征可能是韩国 T1DM 患者的常见表现。
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