预测回肠造口术后脱水再入院的风险:回肠造口术后脱水再入院预测评分。
Predicting the Risk of Readmission From Dehydration After Ileostomy Formation: The Dehydration Readmission After Ileostomy Prediction Score.
机构信息
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Dis Colon Rectum. 2018 Dec;61(12):1410-1417. doi: 10.1097/DCR.0000000000001217.
BACKGROUND
All-cause readmission rates in patients undergoing ileostomy formation are as high as 20% to 30%. Dehydration is a leading cause. No predictive model for dehydration readmission has been described.
OBJECTIVE
The purpose of this study was to develop and validate the Dehydration Readmission After Ileostomy Prediction scoring system to predict the risk of readmission for dehydration after ileostomy formation.
DESIGN
Patients who underwent ileostomy formation were identified using the American College of Surgeons National Surgical Quality Improvement Program data set (2012-2015). Predictors for dehydration were identified using multivariable logistic regression analysis and translated into a point scoring system based on corresponding β-coefficients using 2012-2014 data (derivation). Model discrimination was assessed with receiver operating characteristic curves using 2015 data (validation).
SETTINGS
This study used the American College of Surgeons National Surgical Quality Improvement Program.
PATIENTS
A total of 8064 (derivation) and 3467 patients (validation) were included from the American College of Surgeons National Surgical Quality Improvement Program.
MAIN OUTCOME MEASURES
Dehydration readmission within 30 days of operation was measured.
RESULTS
A total of 8064 patients were in the derivation sample, with 2.9% (20.1% overall) readmitted for dehydration. Twenty-five variables were queried, and 7 predictors were identified with points assigned: ASA class III (4 points), female sex (5 points), IPAA (4 points), age ≥65 years (5 points), shortened length of stay (5 points), ASA class I to II with IBD (7 points), and hypertension (9 points). A 39-point, 5-tier risk category scoring system was developed. The model performed well in derivation (area under curve = 0.71) and validation samples (area under curve = 0.74) and passed the Hosmer-Lemeshow goodness-of-fit test.
LIMITATIONS
Limitations of this study pertained to those of the American College of Surgeons National Surgical Quality Improvement Program, including a lack of generalizability, lack of ileostomy-specific variables, and inability to capture multiple readmission International Classification of Diseases, 9/10 edition, codes.
CONCLUSIONS
The Dehydration Readmission After Ileostomy Prediction score is a validated scoring system that identifies patients at risk for dehydration readmission after ileostomy formation. It is a specific approach to optimize patient factors, implement interventions, and prevent readmissions. See Video Abstract at http://links.lww.com/DCR/A746.
背景
接受回肠造口术的患者的全因再入院率高达 20%至 30%。脱水是主要原因。目前尚未描述用于预测脱水再入院的预测模型。
目的
本研究旨在开发和验证“回肠造口术后脱水再入院预测评分系统”,以预测回肠造口术后因脱水导致的再入院风险。
设计
使用美国外科医师学会国家外科质量改进计划数据集(2012-2015 年)确定接受回肠造口术的患者。使用多变量逻辑回归分析确定脱水的预测因素,并根据相应的β系数使用 2012-2014 年的数据将其转化为评分系统(推导)。使用 2015 年的数据(验证)通过接收者操作特征曲线评估模型的区分能力。
设置
本研究使用美国外科医师学会国家外科质量改进计划。
患者
共纳入来自美国外科医师学会国家外科质量改进计划的 8064 名(推导)和 3467 名患者(验证)。
主要观察指标
术后 30 天内因脱水而再次入院。
结果
共有 8064 例患者纳入推导样本,其中 2.9%(总体为 20.1%)因脱水而再次入院。共询问了 25 个变量,确定了 7 个有分数分配的预测因素:ASA 分级 III 级(4 分)、女性(5 分)、IPAA(4 分)、年龄≥65 岁(5 分)、缩短住院时间(5 分)、ASA 分级 I 至 II 级合并 IBD(7 分)和高血压(9 分)。开发了一个 39 分、5 级风险分类评分系统。该模型在推导(曲线下面积=0.71)和验证样本(曲线下面积=0.74)中表现良好,通过 Hosmer-Lemeshow 拟合优度检验。
局限性
本研究的局限性在于美国外科医师学会国家外科质量改进计划的局限性,包括缺乏普遍性、缺乏回肠造口术特异性变量以及无法捕获多个再入院国际疾病分类,第 9/10 版代码。
结论
回肠造口术后脱水再入院预测评分是一种经过验证的评分系统,可识别出接受回肠造口术的患者发生脱水再入院的风险。这是一种优化患者因素、实施干预措施和预防再入院的具体方法。详见 http://links.lww.com/DCR/A746 上的视频摘要。
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